(Q40242719)

18 September 2017

title

Cytotoxic T lymphocytes from cathepsin B-deficient mice survive normally in vitro and in vivo after encountering and killing target cells (English)

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18 September 2017

6

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18 September 2017

4

Hideo Yagita

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18 September 2017

Katherine Baran

1

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18 September 2017

Annette Ciccone

2

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18 September 2017

Christoph Peters

3

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18 September 2017

Phillip I Bird

5

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18 September 2017

Joseph A Trapani

7

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18 September 2017

language of work or name

English

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publication date

16 August 2006

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Journal of Biological Chemistry

18 September 2017

published in

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18 September 2017

volume

281

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18 September 2017

issue

41

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18 September 2017

page(s)

30485-30491

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

18 September 2017

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Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Functional significance of the perforin/granzyme cell death pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

A central role for Bid in granzyme B-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Lysosomal cysteine proteases: more than scavengers

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Perforin, a pore-forming protein detectable by monoclonal antibodies, is a functional marker for killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

T cell receptor antagonist peptides induce positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

A critical role for granzyme B, in addition to perforin and TNFalpha, in alloreactive CTL-induced mouse pancreatic beta cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Cytoplasts from cytotoxic T lymphocytes are resistant to perforin-mediated lysis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Membrane channel formation by the lymphocyte pore-forming protein: comparison between susceptible and resistant target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Binding of perforin to membranes is sensitive to lipid spacing and not headgroup

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Cytolytic and ion channel-forming properties of the N terminus of lymphocyte perforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Human cathepsin W, a putative cysteine protease predominantly expressed in CD8+ T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

Characterization of murine cathepsin W and its role in cell-mediated cytotoxicity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M602007200

Multiple target cell killing by the cytolytic T lymphocyte and the mechanism of cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602007200

21 January 2018

Identifiers

DOI

10.1074/JBC.M602007200

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18 September 2017

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