(Q40405343)

20 September 2017

Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol (English)

1 reference

20 September 2017

0 references

1 reference

Hui-Ren Zhou

1

1 reference

PubMed ID

15976193

20 September 2017

Zahidul Islam

series ordinal

2

1 reference

PubMed ID

15976193

20 September 2017

James J Pestka

series ordinal

3

1 reference

20 September 2017

23 June 2005

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20 September 2017

Toxicological Sciences

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20 September 2017

87

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20 September 2017

1

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20 September 2017

113-122

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Phosphorylation of HDM2 by Akt.

20 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Bax does not directly participate in the Ca(2+)-induced permeability transition of isolated mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

MAP kinases in the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cytotoxicity induced by nivalenol, deoxynivalenol, and fumonisin B1 in the SF-9 insect cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Kinases: positive and negative regulators of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Overview: apoptotic signaling pathways in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Non-macrocyclic trichothecenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Apoptosis - the p53 network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

p53: 25 years after its discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

The ribotoxic stress response as a potential mechanism for MAP kinase activation in xenobiotic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Deoxynivalenol-induced mitogen-activated protein kinase phosphorylation and IL-6 expression in mice suppressed by fish oil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Relationship of Trichothecene Structure to Cox-2 Induction in the Macrophage: Selective Action of Type B (8-Keto) Trichothecenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Apoptosis induction by T-2 toxin: activation of caspase-9, caspase-3, and DFF-40/CAD through cytosolic release of cytochrome c in HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Molecular mechanism of satratoxin-induced apoptosis in HL-60 cells: activation of caspase-8 and caspase-9 is involved in activation of caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Ribosome-inactivating protein and apoptosis: abrin causes cell death via mitochondrial pathway in Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Decision making by p53: life, death and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Mitochondrial regulation of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Induction of apoptosis by 4-acetyl-12,13-epoxyl-9-trichothecene-3,15-diol from Isaria japonica Yasuda through intracellular reactive oxygen species formation and caspase-3 activation in human leukemia HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Deoxynivalenol: toxicology and potential effects on humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Genotoxic and non-genotoxic pathways of p53 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Trichothecenes in the environment: relevance to human health

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Toxicological features of T-2 toxin and related trichothecenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Modulation of IL-1beta, IL-6 and TNF-alpha secretion and mRNA expression by the trichothecene vomitoxin in the RAW 264.7 murine macrophage cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Surviving the kiss of death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Aerosolized biologic toxins as agents of warfare and terrorism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): dose response and time course

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI234

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFI234

1 reference

20 September 2017

1 reference

PubMed ID

15976193