(Q40486239)

http://europepmc.org/abstract/PMC/5898607

15 June 2018

title

CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells (English)

1 reference

http://europepmc.org/abstract/PMC/5898607

15 June 2018

0 references

1 reference

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Andreas Reinisch

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Joab Camarena

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Daniel P Dever

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Gabriel Washington

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Carmencita E Nicolas

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Mara Pavel-Dinu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Nivi Saxena

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Alec B Wilkens

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Sruthi Mantri

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Nobuko Uchida

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Ayal Hendel

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Anupama Narla

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Ravindra Majeti

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Kenneth I Weinberg

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Matthew H Porteus

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

7 November 2016

1 reference

http://europepmc.org/abstract/PMC/5898607

15 June 2018

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

539

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

7629

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

384-389

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nature20134

4 June 2020

exact match

0 references

cites work

Targeted gene addition in human CD34(+) hematopoietic cells for correction of X-linked chronic granulomatous disease

1 reference

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Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome

17 June 2018

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Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease

17 June 2018

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Towards a new era in medicine: therapeutic genome editing

17 June 2018

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Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory.

17 June 2018

1 reference

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Genome Editing: A New Approach to Human Therapeutics

17 June 2018

1 reference

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Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery.

17 June 2018

1 reference

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Gene therapy returns to centre stage

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Promoterless gene targeting without nucleases ameliorates haemophilia B in mice.

17 June 2018

1 reference

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Easy quantitative assessment of genome editing by sequence trace decomposition

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Engraftment and lineage potential of adult hematopoietic stem and progenitor cells is compromised following short-term culture in the presence of an aryl hydrocarbon receptor antagonist

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Development and applications of CRISPR-Cas9 for genome engineering

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Targeted genome editing in human repopulating haematopoietic stem cells

17 June 2018

1 reference

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Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing

17 June 2018

1 reference

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Nuclease-mediated gene editing by homologous recombination of the human globin locus

17 June 2018

1 reference

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CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

17 June 2018

1 reference

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β-globin gene transfer to human bone marrow for sickle cell disease.

17 June 2018

1 reference

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Gene therapy for PIDs: progress, pitfalls and prospects

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Isolation and functional characterization of human erythroblasts at distinct stages: implications for understanding of normal and disordered erythropoiesis in vivo

17 June 2018

1 reference

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

17 June 2018

1 reference

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Universal real-time PCR for the detection and quantification of adeno-associated virus serotype 2-derived inverted terminal repeat sequences

17 June 2018

1 reference

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Hematopoiesis: a human perspective

17 June 2018

1 reference

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AAV-mediated gene targeting methods for human cells

17 June 2018

1 reference

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Ex vivo gene transfer and correction for cell-based therapies

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Hematopoietic stem cell: self-renewal versus differentiation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

17 June 2018

1 reference

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Collaboration and competition between DNA double-strand break repair pathways

17 June 2018

1 reference

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Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

17 June 2018

1 reference

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Gene therapy: therapeutic gene causing lymphoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Adeno-associated virus vectors integrate at chromosome breakage sites

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Chimeric nucleases stimulate gene targeting in human cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Human gene targeting by viral vectors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Isolation of a candidate human hematopoietic stem-cell population

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Hematopoietic stem and progenitor cells acquire distinct DNA-hypermethylation during in vitro culture

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5898607

The total marrow mass of the mouse: a simplified method of measurement

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27820943

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Safety of retroviral gene marking with a truncated NGF receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27820943

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE20134

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27820943%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference