(Q40504128)

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The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase

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Europe PubMed Central

PubMed publication ID

21 September 2017

The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase (English)

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Europe PubMed Central

PubMed publication ID

21 September 2017

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Michael C. Ostrowski

6

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Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Latha P Ganesan

1

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Europe PubMed Central

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21 September 2017

Guo Wei

2

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Europe PubMed Central

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21 September 2017

Ruma A Pengal

3

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Europe PubMed Central

PubMed publication ID

21 September 2017

Leni Moldovan

4

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Europe PubMed Central

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21 September 2017

Nicanor Moldovan

5

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Europe PubMed Central

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21 September 2017

Susheela Tridandapani

7

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Europe PubMed Central

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21 September 2017

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publication date

12 October 2004

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21 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

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21 September 2017

279

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Europe PubMed Central

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21 September 2017

52

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21 September 2017

54416-54425

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Europe PubMed Central

PubMed publication ID

21 September 2017

Mechanisms of phagocytosis in macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

IgG Fc receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Signal transduction by human-restricted Fc gamma RIIa involves three distinct cytoplasmic kinase families leading to phagocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Lyn and Syk kinases are sequentially engaged in phagocytosis mediated by Fc gamma R.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

The Src homology 2 domain-containing inositol 5-phosphatase negatively regulates Fcgamma receptor-mediated phagocytosis through immunoreceptor tyrosine-based activation motif-bearing phagocytic receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Modulation of immune complex-induced inflammation in vivo by the coordinate expression of activation and inhibitory Fc receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Regulated expression and inhibitory function of Fcgamma RIIb in human monocytic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Differential modulation of stimulatory and inhibitory Fc gamma receptors on human monocytes by Th1 and Th2 cytokines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Phosphoinositide 3-Kinase and p72 Noncovalently Associate with the Low Affinity Fc Receptor on Human Platelets through an Immunoreceptor Tyrosine-based Activation Motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

A requirement for phosphatidylinositol 3-kinase in pseudopod extension

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Integrin-linked kinase regulates phosphorylation of serine 473 of protein kinase B by an indirect mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Akt activation by growth factors is a multiple-step process: the role of the PH domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

PKB binding proteins. Getting in on the Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

PKB/AKT: functional insights from genetic models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

TGF-beta 1 suppresses [correction of supresses] myeloid Fc gamma receptor function by regulating the expression and function of the common gamma-subunit.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

United at last: the tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Identification of a conserved motif required for mTOR signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Structural and functional analysis of pp70S6k

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

SHIP-2 Inositol Phosphatase Is Inducibly Expressed in Human Monocytes and Serves to Regulate Fcγ Receptor-mediated Signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Induction of NF-kappaB by the Akt/PKB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Role of the p70(S6K) pathway in regulating the actin cytoskeleton and cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Cellular function of p70S6K: a role in regulating cell motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

A p85 subunit-independent p110alpha PI 3-kinase colocalizes with p70 S6 kinase on actin stress fibers and regulates thrombin-stimulated stress fiber formation in swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Vav regulates activation of Rac but not Cdc42 during FcgammaR-mediated phagocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408188200

21 January 2018

Identifiers

10.1074/JBC.M408188200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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