(Q40663884)

22 September 2017

title

Radiation increases the activity of oncolytic adenovirus cancer gene therapy vectors that overexpress the ADP (E3-11.6K) protein (English)

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adaptive radiation therapy

22 September 2017

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2

Vera Tarakanova

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22 September 2017

Karoly Toth

1

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22 September 2017

Konstantin Doronin

3

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22 September 2017

Peter Ward

4

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22 September 2017

Mohan Kuppuswamy

5

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22 September 2017

Jacob E Locke

6

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22 September 2017

Julie E Dawson

7

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22 September 2017

Han J Kim

8

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22 September 2017

William S M Wold

9

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22 September 2017

publication date

1 March 2003

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22 September 2017

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22 September 2017

volume

10

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22 September 2017

issue

3

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22 September 2017

page(s)

193-200

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https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700555

22 September 2017

exact match

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cites work

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Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway

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21 January 2018

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21 January 2018

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21 January 2018

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Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?

21 January 2018

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Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).

21 January 2018

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Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein

21 January 2018

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A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

21 January 2018

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The E3-11.6-kDa adenovirus death protein (ADP) is required for efficient cell death: characterization of cells infected with adp mutants

21 January 2018

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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

21 January 2018

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Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization

21 January 2018

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a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

21 January 2018

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Inhibition of nuclear factor-kappaB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis

21 January 2018

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Regulation of the 26S proteasome by adenovirus E1A

21 January 2018

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21 January 2018

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Inhibition of NF-kappaB, clonogenicity, and radiosensitivity of human cancer cells

21 January 2018

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The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle

21 January 2018

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7 January 2021

p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700555

7 January 2021

An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700555

7 January 2021

Overexpression of the ADP (E3-11.6K) protein increases cell lysis and spread of adenovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700555

7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7700555

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Dimensions Publication ID

22 September 2017

1046416160

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