(Q40755303)

English

Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist

scientific article published on 4 February 2013

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist (English)

1 reference

Europe PubMed Central

23 September 2017

Alzheimer's disease

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1 reference

based on heuristic

inferred from title

author name string

Maria B Goncalves

1

1 reference

Europe PubMed Central

23 September 2017

Earl Clarke

2

1 reference

Europe PubMed Central

23 September 2017

Carl Hobbs

3

1 reference

Europe PubMed Central

23 September 2017

Tony Malmqvist

4

1 reference

Europe PubMed Central

23 September 2017

Robert Deacon

5

1 reference

Europe PubMed Central

23 September 2017

Julian Jack

6

1 reference

Europe PubMed Central

23 September 2017

Jonathan P T Corcoran

7

1 reference

Europe PubMed Central

23 September 2017

language of work or name

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publication date

4 February 2013

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Europe PubMed Central

23 September 2017

European Journal of Neuroscience

1 reference

Europe PubMed Central

23 September 2017

37

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Europe PubMed Central

23 September 2017

7

1 reference

Europe PubMed Central

23 September 2017

1182-1192

1 reference

Europe PubMed Central

23 September 2017

AP-2β regulates amyloid beta-protein stimulation of apolipoprotein E transcription in astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

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ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

1 reference

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24 September 2017

Neuropathological alterations in Alzheimer disease

1 reference

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24 September 2017

Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?

1 reference

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Soluble Aβ oligomer production and toxicity

1 reference

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Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases

1 reference

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'Clinical trials in Alzheimer's disease': immunotherapy approaches

1 reference

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Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motif

1 reference

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24 September 2017

Ca2+ dysfunction in neurodegenerative disorders: Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Decreased clearance of CNS beta-amyloid in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Distribution of retinoic acid receptor-α immunoreactivity in the human hypothalamus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

The molecular physiology of nuclear retinoic acid receptors. From health to disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Inflammation, microglia, and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Integrating retinoic acid signaling with brain function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Collagen VI protects neurons against Abeta toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Synaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Retinoic acid regulates RARalpha-mediated control of translation in dendritic RNA granules during homeostatic synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

ApoE promotes the proteolytic degradation of Abeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Retinoic acid in the development, regeneration and maintenance of the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Intracellular amyloid-beta in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Is 9-cis-retinoic acid the endogenous ligand for the retinoic acid-X receptor?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Amyloid beta peptide as a physiological modulator of neuronal 'A'-type K+ current

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Role of retinoid signalling in the adult brain

1 reference

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24 September 2017

The role of inflammation in Alzheimer's disease

1 reference

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24 September 2017

Neprilysin regulates amyloid Beta peptide levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Evidence for defective retinoid transport and function in late onset Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

24 September 2017

Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

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1 reference

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24 September 2017

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1 reference

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1 reference

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24 September 2017

Conditional RARα knockout mice reveal acute requirement for retinoic acid and RARα in homeostatic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

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Degradation of amyloid beta-protein by a metalloprotease secreted by microglia and other neural and non-neural cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

25 September 2017

Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

25 September 2017

Retinoic acid receptor-α signalling antagonizes both intracellular and extracellular amyloid-β production and prevents neuronal cell death caused by amyloid-β.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

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Decrease in calcium concentration triggers neuronal retinoic acid synthesis during homeostatic synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

17 June 2018

The production of amyloid beta peptide is a critical requirement for the viability of central neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

17 June 2018

Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer m

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

19 August 2018

Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

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A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord

1 reference

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T-maze alternation in the rodent.

1 reference

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19 August 2018

Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.

1 reference

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1 reference

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19 August 2018

Disruption of the retinoid signalling pathway causes a deposition of amyloid beta in the adult rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

19 August 2018

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

19 August 2018

Retinoic acid hydroxylase (CYP26) is a key enzyme in neuronal differentiation of embryonal carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3655538

19 August 2018

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

1 reference

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19 August 2018

Effect of a disulfiram metabolite on retinaldehyde metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23379615

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1111/EJN.12142

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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