(Q40787920)

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Caffeine sensitizes human H358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of BAX protein.

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10 November 2019

Caffeine sensitizes human H358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of BAX protein (English)

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11489880%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Dubrez Laurence

1

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10 November 2019

2

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10 November 2019

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10 November 2019

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Hurbin A

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10 November 2019

Favrot MC

5

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10 November 2019

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6 August 2001

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10 November 2019

Journal of Biological Chemistry

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10 November 2019

276

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10 November 2019

42

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10 November 2019

38980-38987

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10 November 2019

Defying death after DNA damage.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Maintenance of genomic integrity by p53: complementary roles for activated and non-activated p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Cell death and cancer: replacement of apoptotic genes and inactivation of death suppressor genes in therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Mechanisms of p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Control of apoptosis and mitotic spindle checkpoint by survivin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Superinduction of wild-type p53 protein after 2-methoxyestradiol treatment of Ad5p53-transduced cells induces tumor cell apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Radiation-induced apoptosis is not enhanced by expression of either p53 or BAX in SW626 ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

The tumor suppressor p53 can both stimulate and inhibit ultraviolet light-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Conformation of the Bax C-terminus regulates subcellular location and cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Structure of Bax: coregulation of dimer formation and intracellular localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Mechanism of caffeine-induced checkpoint override in fission yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102683200

21 January 2018

Identifiers

10.1074/JBC.M102683200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11489880%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11489880%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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