(Q42484376)

1 November 2017

Tissue and cell-specific expression of the p53-target genes: bax, fas, mdm2 and waf1/p21, before and following ionising irradiation in mice (English)

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1 November 2017

V Bouvard

1

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1 November 2017

T Zaitchouk

2

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1 November 2017

M Vacher

3

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1 November 2017

A Duthu

4

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1 November 2017

M Canivet

5

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1 November 2017

C Choisy-Rossi

6

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1 November 2017

M Nieruchalski

7

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1 November 2017

E May

8

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1 November 2017

language of work or name

English

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publication date

1 February 2000

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1 November 2017

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1 November 2017

19

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1 November 2017

649-660

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1 November 2017

5

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203366

1 November 2017

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cites work

Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Molecular characterization of the hdm2-p53 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

A transcriptionally active DNA-binding site for human p53 protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Wild-type p53 can down-modulate the activity of various promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

p53 mutations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Identification of p53 as a sequence-specific DNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Overexpression of the Bcl-2 protein increases the half-life of p21Bax

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Wild-type p53 negatively regulates the expression of a microtubule-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Bcl-2 family proteins and mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Constitutive expression of the cyclin-dependent kinase inhibitor p21 is transcriptionally regulated by the tumor suppressor protein p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Role of Fas-mediated cell death in the regulation of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

mdm2 expression is induced by wild type p53 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

Further characterisation of the p53 responsive element--identification of new candidate genes for trans-activation by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

p53 in growth control and neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

Differential regulation of the p21/WAF-1 and mdm2 genes after high-dose UV irradiation: p53-dependent and p53-independent regulation of the mdm2 gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203366

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203366

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Dimensions Publication ID

1 November 2017

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1 reference