(Q41635852)

5 October 2017

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title

Pharmacology and pharmacokinetics of methotrexate in rheumatic disease. Practical issues in treatment and design (English)

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5 October 2017

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Hillson JL

1

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5 October 2017

Furst DE

series ordinal

2

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5 October 2017

publication date

1 November 1997

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Rheumatic Diseases Clinics of North America

5 October 2017

published in

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5 October 2017

volume

23

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5 October 2017

issue

4

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5 October 2017

page(s)

757-778

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Prolongation and enhancement of serum methotrexate concentrations by probenecid

5 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate-induced renal failure and ineffectiveness of peritoneal dialysis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Differences in methotrexate and 7-hydroxymethotrexate inhibition of folate-dependent enzymes of purine nucleotide biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Polygammaglutamyl metabolites of methotrexate.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

The clinical pharmacology of methotrexate.new applications of an old drug

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Threshold Methotrexate Concentration for In Vivo Inhibition of DNA Synthesis in Normal and Tumorous Target Tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Studies on the folic acid vitamins. IV. The persistence of amethopterin in mammalian tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Effect of protein-calorie malnutrition on methotrexate pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate treatment every other week in patients with juvenile chronic arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Total and free methotrexate pharmacokinetics, with and without piroxicam, in rheumatoid arthritis patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

The effect of methotrexate and hydroxyurea on neutrophil chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate Hepatotoxicity in Psoriasis--Comparison of Different Dose Regimens

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate toxicity precipitated by azapropazone

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Carboxypeptidase G2 rescue after high-dose methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Folate supplementation and methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Low-dose methotrexate kinetics in arthritis.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Total and free methotrexate pharmacokinetics in rheumatoid arthritis patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Synthesis and biologic evaluation of 7-hydroxymethotrexate, 7-methylaminopterin, and 7-methylmethotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Persistence of amethopterin in normal mouse tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate and nonsteroidal antiinflammatory drug interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Effect of aspirin and sulindac on methotrexate clearance

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate toxicity: Correlation with duration of administration, plasma levels, dose and excretion pattern

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate and trimethoprim-sulphamethoxazole--a potentially hazardous combination.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Combination of methotrexate and sulphasalazine vs methotrexate alone: a randomized open clinical trial in rheumatoid arthritis patients resistant to sulphasalazine therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Entero-hepatic cycling of methotrexate estimated by use of the D-isomer as a reference marker

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Pharmacokinetics of low-dose methotrexate in rheumatoid arthritis patients

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Hemodialysis and enzymatic cleavage of methotrexate in man

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Successful carboxypeptidase G2 rescue in delayed MTX-elimination due to renal failure

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Stoichiometric inhibition of mammalian dihydrofolate reductase by the γ-glutamyl metabolite of methotrexate, 4-amino-4-deoxy-N10-methylpteroylglutamyl-γ-glutamate

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Accumulation of methotrexate diglutamate in human liver during methotrexate therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Pharmacokinetics of methotrexate in continuous ambulatory peritoneal dialysis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Pancytopenia and methotrexate with trimethoprim-sulfamethoxazole

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

The pharmacology and clinical use of methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

The effect of food on the absorption of methotrexate sodium tablets in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Every-other-week methotrexate in patients with rheumatoid arthritis. A double-blind, placebo-controlled prospective study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate metabolism analysis in blood and liver of rheumatoid arthritis patients. Association with hepatic folate deficiency and formation of polyglutamates

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

The effect of organic acids on renal clearance of methotrexate in man

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Clinical pharmacology of oral intermediate-dose methotrexate with or without probenecid

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Acute renal failure due to concomitant action of methotrexate and indomethacin

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

The synergistic effect of salicylates on methotrexate toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Enzymatic synthesis and function of folylpolyglutamates

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate induced liver disease in psoriasis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Role of thymidylate synthetase activity in development of methotrexate cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate and sulfasalazine combination therapy: is it worth the risk?

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Near fatal drug interactions with methotrexate given for psoriasis.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Biliary elimination of low-dose methotrexate in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Effect of food on the bioavailability of low-dose methotrexate in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Antiproliferative effects of methotrexate on peripheral blood mononuclear cells

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Inhibition of dihydrofolic reductase by aminopterin and amethopterin

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Intestinal absorption in patients with rheumatoid arthritis treated with methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate--the relationship between dose and clinical effect

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

The pharmacokinetics of methotrexate and its 7-hydroxy metabolite in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Gastrointestinal absorption of folates and antifolates

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Unsubstantiated "risk" of antifolate toxicity with combination methotrexate and sulfasalazine therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

pH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Fatal interaction between methotrexate and naproxen

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Pharmacokinetics of methotrexate and 7-hydroxy-methotrexate in plasma and bone marrow of children receiving low-dose oral methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Coadministration of naproxen and low-dose methotrexate in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Aspirin alters methotrexate disposition in rheumatoid arthritis patients

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Pancytopenia induced by the interaction between methotrexate and trimethoprim-sulfamethoxazole

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Methotrexate disposition following concomitant administration of ketoprofen, piroxicam and flurbiprofen in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Effective clearance of methotrexate using high-flux hemodialysis membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Toxicity and serum levels of methotrexate in children with juvenile rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Carboxypeptidase-G2 rescue in a patient with high dose methotrexate-induced nephrotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

Successful carboxypeptidase G2 rescue in delayed methotrexate elimination due to renal failure.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970359-8

7 January 2021

10.1016/S0889-857X(05)70359-8

Identifiers

DOI

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5 October 2017

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