(Q41899379)

English

Imatinib Upregulates Compensatory Integrin Signaling in a Mouse Model of Gastrointestinal Stromal Tumor and Is More Effective When Combined with Dasatinib

scientific article published on August 24, 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Imatinib Upregulates Compensatory Integrin Signaling in a Mouse Model of Gastrointestinal Stromal Tumor and Is More Effective When Combined with Dasatinib (English)

1 reference

10.1158/1541-7786.MCR-10-0065

https://api.crossref.org/works/10.1158/1541-7786.MCR-10-0065

22 June 2024

gastrointestinal stromal tumor

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

signal transduction

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

positive regulation of biological process

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

4

object named as

Darren Veach

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

Cristina R Antonescu

8

object named as

Cristina R. Antonescu

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

author name string

Ferdinand Rossi

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Yasemin Yozgat

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Elisa de Stanchina

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Bayard Clarkson

5

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Katia Manova

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Peter Besmer

9

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Filippo G. Giancotti

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

language of work or name

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National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20736294

22 June 2024

publication date

24 August 2010

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

full work available at URL

http://mcr.aacrjournals.org/content/8/9/1271.full.pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

http://mcr.aacrjournals.org/cgi/content/abstract/8/9/1271

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20736294/?tool=EBI

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20736294/pdf/?tool=EBI

Portable Document Format

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

https://europepmc.org/articles/PMC2952175

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

https://europepmc.org/articles/PMC2952175?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

https://doi.org/10.1158/1541-7786.mcr-10-0065

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736294

22 June 2024

https://aacrjournals.org/mcr/article-pdf/8/9/1271/3146829/1271.pdf

Portable Document Format

1 reference

10.1158/1541-7786.MCR-10-0065

https://api.crossref.org/works/10.1158/1541-7786.MCR-10-0065

22 June 2024

Molecular Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

8

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

9

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

1271-1283

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

1 reference

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Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

1 reference

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SGX393 inhibits the CML mutant Bcr-AblT315I and preempts in vitro resistance when combined with nilotinib or dasatinib.

1 reference

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5 June 2018

Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention

1 reference

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5 June 2018

A quantitative analysis of kinase inhibitor selectivity

1 reference

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Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility.

1 reference

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1 reference

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5 June 2018

Second line therapies for the treatment of gastrointestinal stromal tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Signalling via integrins: implications for cell survival and anticancer strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Integrin-regulated FAK-Src signaling in normal and cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

L1 (CD171) is highly expressed in gastrointestinal stromal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Integrins and Src: dynamic duo of adhesion signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Integrin signalling during tumour progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Overriding imatinib resistance with a novel ABL kinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Molecular targets for tumour progression in gastrointestinal stromal tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Focal adhesion kinase: the first ten years

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

1 reference

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5 June 2018

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

Thrombospondin-1 acts via IAP/CD47 to synergize with collagen in alpha2beta1-mediated platelet activation

1 reference

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5 June 2018

Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952175

5 June 2018

SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain

1 reference

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5 June 2018

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

1 reference

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A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins

1 reference

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Lyn associates with the juxtamembrane region of c-Kit and is activated by stem cell factor in hematopoietic cell lines and normal progenitor cells

1 reference

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Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.

1 reference

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Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells

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1 reference

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1 reference

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1 reference

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Sorafenib Inhibits the Imatinib-Resistant KITT670I Gatekeeper Mutation in Gastrointestinal Stromal Tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20736294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KIT oncoprotein interactions in gastrointestinal stromal tumors: therapeutic relevance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20736294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1541-7786.MCR-10-0065

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

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