(Q41980019)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

siPools: highly complex but accurately defined siRNA pools eliminate off-target effects (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

author name string

Michael Hannus

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Michaela Beitzinger

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Marie-Theresa Weickert

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Rainer Spang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Stefan Hannus

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Gunter Meister

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

publication date

29 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

published in

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

page(s)

8049-8061

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

19 March 2020

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4081087

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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RNAi factors are present and active in human cell nuclei

5 June 2018

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Argonaute proteins: functional insights and emerging roles

5 June 2018

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A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

5 June 2018

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Dicer is dispensable for asymmetric RISC loading in mammals

5 June 2018

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Chemical modification of siRNA bases to probe and enhance RNA interference

5 June 2018

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Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes

5 June 2018

1 reference

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Increased siRNA duplex stability correlates with reduced off-target and elevated on-target effects

5 June 2018

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5 June 2018

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Gene silencing by microRNAs: contributions of translational repression and mRNA decay

5 June 2018

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Vigilance and validation: Keys to success in RNAi screening

5 June 2018

1 reference

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A framework for oligonucleotide microarray preprocessing.

5 June 2018

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The widespread regulation of microRNA biogenesis, function and decay

5 June 2018

1 reference

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Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo

5 June 2018

1 reference

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Argonaute proteins at a glance

5 June 2018

1 reference

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A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

5 June 2018

1 reference

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Genomic screening with RNAi: results and challenges

5 June 2018

1 reference

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HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells

5 June 2018

1 reference

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Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

5 June 2018

1 reference

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Minimizing off-target effects by using diced siRNAs for RNA interference

5 June 2018

1 reference

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E. coli RNase III(E38A) generates discrete-sized products from long dsRNA.

5 June 2018

1 reference

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Origins and Mechanisms of miRNAs and siRNAs

5 June 2018

1 reference

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MicroRNAs: target recognition and regulatory functions

5 June 2018

1 reference

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Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs

5 June 2018

1 reference

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A three-dimensional view of the molecular machinery of RNA interference

5 June 2018

1 reference

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On the road to reading the RNA-interference code

5 June 2018

1 reference

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Importance of translation and nonnucleolytic ago proteins for on-target RNA interference

5 June 2018

1 reference

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A multifunctional human Argonaute2-specific monoclonal antibody

5 June 2018

1 reference

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Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.

5 June 2018

1 reference

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Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity

5 June 2018

1 reference

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Argonaute proteins: key players in RNA silencing

5 June 2018

1 reference

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Improved silencing properties using small internally segmented interfering RNAs

5 June 2018

1 reference

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Identification of human microRNA targets from isolated argonaute protein complexes

5 June 2018

1 reference

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Argonaute proteins: mediators of RNA silencing

5 June 2018

1 reference

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Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies

5 June 2018

1 reference

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Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

5 June 2018

1 reference

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Comparison of siRNA-induced off-target RNA and protein effects

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

5 June 2018

1 reference

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Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

5 June 2018

1 reference

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

5 June 2018

1 reference

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RNAi as a treatment for HIV-1 infection.

5 June 2018

1 reference

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Cleavage of the siRNA passenger strand during RISC assembly in human cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

5 June 2018

1 reference

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

5 June 2018

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

5 June 2018

1 reference

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Mechanisms of gene silencing by double-stranded RNA

5 June 2018

1 reference

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Argonaute2 is the catalytic engine of mammalian RNAi

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

siRNAs: applications in functional genomics and potential as therapeutics

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Variance stabilization applied to microarray data calibration and to the quantification of differential expression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Argonaute2, a link between genetic and biochemical analyses of RNAi

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Improved northern blot method for enhanced detection of small RNA.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Specific and potent RNAi in the nucleus of human cells

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081087

Production of endoribonuclease-prepared short interfering RNAs for gene silencing in mammalian cells

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKU480

Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24875475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKU480

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24875475%20AND%20SRC:MED&resulttype=core&format=json