(Q42290882)

20 October 2017

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling (English)

1 reference

G protein-coupled receptor

20 October 2017

0 references

author

Philippe P. Roux

13

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20 October 2017

16

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20 October 2017

Hiroyuki Kobayashi

7

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Franziska M Heydenreich

object named as

Franziska M Heydenreich

10

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Dmitry B Veprintsev

object named as

Dmitry B Veprintsev

14

0 references

Alexandre Beautrait

object named as

Alexandre Beautrait

1

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author name string

Justine S Paradis

2

1 reference

20 October 2017

Brandon Zimmerman

3

1 reference

20 October 2017

Jenna Giubilaro

4

1 reference

20 October 2017

Ljiljana Nikolajev

5

1 reference

20 October 2017

Sylvain Armando

6

1 reference

20 October 2017

Lama Yamani

8

1 reference

20 October 2017

Yoon Namkung

9

1 reference

20 October 2017

Etienne Khoury

11

1 reference

20 October 2017

Martin Audet

12

1 reference

20 October 2017

Stéphane A Laporte

15

1 reference

20 October 2017

language of work or name

English

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publication date

18 April 2017

1 reference

20 October 2017

Nature Communications

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20 October 2017

8

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20 October 2017

15054

1 reference

Creative Commons Attribution 4.0 International

20 October 2017

start time

1 April 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms15054

0 references

cites work

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Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET

26 October 2017

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β-Arrestin drives MAP kinase signalling from clathrin-coated structures after GPCR dissociation.

26 October 2017

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Persistent cAMP Signaling by Internalized LH Receptors in Ovarian Follicles

26 October 2017

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Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression.

26 October 2017

1 reference

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Spatial and Temporal Aspects of Signaling by G-Protein-Coupled Receptors

26 October 2017

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G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins from endosomes

26 October 2017

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26 October 2017

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Differential regulation of endosomal GPCR/β-arrestin complexes and trafficking by MAPK

26 October 2017

1 reference

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GPCR signaling along the endocytic pathway

26 October 2017

1 reference

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Genome engineering using the CRISPR-Cas9 system

26 October 2017

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Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis

26 October 2017

1 reference

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Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.

26 October 2017

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Advances in analysis of low signal-to-noise images link dynamin and AP2 to the functions of an endocytic checkpoint

26 October 2017

1 reference

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Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

26 October 2017

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Search for inhibitors of endocytosis: Intended specificity and unintended consequences

26 October 2017

1 reference

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Conformational biosensors reveal GPCR signalling from endosomes.

26 October 2017

1 reference

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Pituitary adenylate cyclase 1 receptor internalization and endosomal signaling mediate the pituitary adenylate cyclase activating polypeptide-induced increase in guinea pig cardiac neuron excitability

26 October 2017

1 reference

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Pitstop 2 is a potent inhibitor of clathrin-independent endocytosis

26 October 2017

1 reference

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Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition

26 October 2017

1 reference

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Endocytosis promotes rapid dopaminergic signaling

26 October 2017

1 reference

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Molecular mechanism and physiological functions of clathrin-mediated endocytosis

26 October 2017

1 reference

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β-Arrestin-mediated receptor trafficking and signal transduction

26 October 2017

1 reference

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A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Beyond desensitization: physiological relevance of arrestin-dependent signaling.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Signaling by internalized G-protein-coupled receptors.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Endocytosis and signalling: intertwining molecular networks

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Persistent cAMP-signals triggered by internalized G-protein-coupled receptors

26 October 2017

1 reference

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Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles

26 October 2017

1 reference

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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway

26 October 2017

1 reference

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Regulation of GPCRs by endocytic membrane trafficking and its potential implications

26 October 2017

1 reference

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Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

26 October 2017

1 reference

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Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

The V2 vasopressin receptor stimulates ERK1/2 activity independently of heterotrimeric G protein signalling

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Dynasore, a cell-permeable inhibitor of dynamin

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Transduction of receptor signals by beta-arrestins

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

The molecular acrobatics of arrestin activation

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-arrestin binging site in beta 2-adaptin

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Characterization of G protein-coupled receptor regulation in antisense mRNA-expressing cells with reduced arrestin levels

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

A serine cluster prevents recycling of the V2 vasopressin receptor

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Modulation of the arrestin-clathrin interaction in cells. Characterization of beta-arrestin dominant-negative mutants

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor kinase specificity

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Mutations in human dynamin block an intermediate stage in coated vesicle formation

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Role of ßarrestins in bradykinin B2 receptor-mediated signalling.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399295

Pharmacological Chaperones Restore Function to MC4R Mutants Responsible for Severe Early-Onset Obesity

17 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15054

Oxytocin and Vasopressin V1a and V2 Receptors Form Constitutive Homo- and Heterodimers during Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15054

Recruitment of activated G protein-coupled receptors to pre-existing clathrin-coated pits in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15054

7 January 2021

inferred from DOI database lookup

Cholesterol oxidation switches the internalization pathway of endothelin receptor type A from caveolae to clathrin-coated pits in Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15054

7 January 2021

inferred from DOI database lookup

Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15054

7 January 2021

inferred from DOI database lookup

Protein-protein interaction inhibitors get into the groove

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28416805

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCOMMS15054

1 reference

20 October 2017

0 references

1 reference

20 October 2017

1 reference