(Q42370203)

English

Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: insights into substrate specificity and membrane bound structure-function

scientific article published on 3 December 2006

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: insights into substrate specificity and membrane bound structure-function (English)

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

0 references

mutational analysis

1 reference

based on heuristic

inferred from title

Andrew J Annalora

object named as

Andrew J Annalora

1

0 references

author name string

Ekaterina Bobrovnikov-Marjon

2

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Rita Serda

3

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Andrzej Pastuszyn

4

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Sandra E Graham

5

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

Craig B Marcus

6

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

John L Omdahl

7

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

language of work or name

0 references

publication date

3 December 2006

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

Archives of Biochemistry and Biophysics

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

460

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

2

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

262-273

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

The ins and outs of cytochrome P450s.

1 reference

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29 May 2018

CYP24, the enzyme that catabolizes the antiproliferative agent vitamin D, is increased in lung cancer

1 reference

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Promise of vitamin D analogues in the treatment of hyperproliferative conditions

1 reference

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29 May 2018

Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: amino acid residues responsible for species-based difference of CYP24A1 between humans and rats

1 reference

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29 May 2018

Structural motif-based homology modeling of CYP27A1 and site-directed mutational analyses affecting vitamin D hydroxylation

1 reference

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1 reference

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Expression of VDR and CYP24A1 mRNA in human tumors

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Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

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Non-Michaelis-Menten kinetics in cytochrome P450-catalyzed reactions

1 reference

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The role of Vitamin D3 metabolism in prostate cancer

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Vitamin D and breast cancer: insights from animal models

1 reference

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29 May 2018

Metabolism of vitamin D3 by cytochromes P450

1 reference

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29 May 2018

CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis

1 reference

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29 May 2018

Enzymes involved in the activation and inactivation of vitamin D.

1 reference

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Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

1 reference

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A survey of active site access channels in cytochromes P450.

1 reference

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The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution

1 reference

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29 May 2018

Structural commonalities among integral membrane enzymes

1 reference

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29 May 2018

Clinical significance of the overexpression of the candidate oncogene CYP24 in esophageal cancer

1 reference

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29 May 2018

Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site

1 reference

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29 May 2018

An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution

1 reference

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29 May 2018

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

1 reference

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29 May 2018

SWISS-MODEL: An automated protein homology-modeling server

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978416

29 May 2018

Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978416

29 May 2018

Hydroxylase enzymes of the vitamin D pathway: expression, function, and regulation

1 reference

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29 May 2018

Pivotal role of water in the mechanism of P450BM-3

1 reference

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Differential activities of 1alpha,25-dihydroxy-16-ene-vitamin D(3) analogs and their 3-epimers on human promyelocytic leukemia (HL-60) cell differentiation and apoptosis

1 reference

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How do substrates enter and products exit the buried active site of cytochrome P450cam? 1. Random expulsion molecular dynamics investigation of ligand access channels and mechanisms.

1 reference

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Dual metabolic pathway of 25-hydroxyvitamin D3 catalyzed by human CYP24

1 reference

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Characterization of 3-epi-1alpha,25-dihydroxyvitamin D3 involved in 1alpha,25-dihydroxyvitamin D3 metabolic pathway in cultured cell lines

1 reference

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Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

1 reference

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A comprehensive comparison of multiple sequence alignment programs

1 reference

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VMD: visual molecular dynamics

1 reference

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Human 25-hydroxyvitamin D3-24-hydroxylase, a multicatalytic enzyme

1 reference

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Cholesterol binding to cytochrome P450 7A1, a key enzyme in bile acid biosynthesis

1 reference

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The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

1 reference

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Affinity labeling of rat cytochrome P450C24 (CYP24) and identification of Ser57 as an active site residue

1 reference

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Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity.

1 reference

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1 reference

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Membrane-protein interactions contribute to efficient 27-hydroxylation of cholesterol by mitochondrial cytochrome P450 27A1.

1 reference

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Distinct binding of cholesterol and 5beta-cholestane-3alpha,7alpha,12alpha-triol to cytochrome P450 27A1: evidence from modeling and site-directed mutagenesis studies

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/17207766

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.ABB.2006.11.018

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 October 2017

ResearchGate publication ID

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