(Q42645907)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Selective, rapid and optically switchable regulation of protein function in live mammalian cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

John R James

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

author name string

Sebastian Essig

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Kathrin Lang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Jason W Chin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

publication date

18 May 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

554-561

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nchem.2253

17 February 2020

exact match

0 references

cites work

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Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973)

27 May 2018

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The clinical development of MEK inhibitors

27 May 2018

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Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal

27 May 2018

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Cellular incorporation of unnatural amino acids and bioorthogonal labeling of proteins

27 May 2018

1 reference

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CRISPR-Cas systems for editing, regulating and targeting genomes

27 May 2018

1 reference

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Reversible photocontrol of biological systems by the incorporation of molecular photoswitches

27 May 2018

1 reference

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Developing irreversible inhibitors of the protein kinase cysteinome

27 May 2018

1 reference

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Protein organic chemistry and applications for labeling and engineering in live-cell systems

27 May 2018

1 reference

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Second-generation covalent TMP-tag for live cell imaging

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Biophysical mechanism of T-cell receptor triggering in a reconstituted system

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Genetic Encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

27 May 2018

1 reference

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Genetically encoded tetrazine amino acid directs rapid site-specific in vivo bioorthogonal ligation with trans-cyclooctenes

27 May 2018

1 reference

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Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

27 May 2018

Optochemical genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Organic synthesis toward small-molecule probes and drugs

27 May 2018

1 reference

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Bioorthogonal chemistry: fishing for selectivity in a sea of functionality

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

The structure, regulation, and function of ZAP-70.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?

27 May 2018

1 reference

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Activity-based protein profiling: from enzyme chemistry to proteomic chemistry

27 May 2018

1 reference

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Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding

27 May 2018

1 reference

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Structure-guided development of affinity probes for tyrosine kinases using chemical genetics

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Dependence of Effective Molarity on Linker Length for an Intramolecular Protein−Ligand System

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Azobenzene as conformational switch in model peptides.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Allosteric control of an ionotropic glutamate receptor with an optical switch.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

BRAF mutation predicts sensitivity to MEK inhibition

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Targeting the mitogen-activated protein kinase cascade to treat cancer

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

MEK1 and MEK2, different regulators of the G1/S transition.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Tethering: fragment-based drug discovery

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

The Ras-Raf-MEK-ERK pathway in the treatment of cancer

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Multivalent inhibition of AB(5) toxins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Recent advances in chemical approaches to the study of biological systems

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

A chemical switch for inhibitor-sensitive alleles of any protein kinase

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Transformation of mammalian cells by constitutively active MAP kinase kinase

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Simplified models for heterobivalent ligand binding: when are they applicable and which are the factors that affect their target residence time

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Expanding the genetic code of Drosophila melanogaster

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Amino acids for Diels-Alder reactions in living cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Chemical genetics: where genetics and pharmacology meet

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click Reaction

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4673907

Bioorthogonal Reactions for Labeling Proteins

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26100803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fluorescence imaging of azobenzene photoswitching in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26100803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEM.2253

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26100803%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

26100803

1 reference