(Q42803394)

English

Human gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN PKR-induced apoptosis.

scientific article published on 13 April 2006

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scholarly article

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19 January 2020

Human gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN PKR-induced apoptosis (English)

1 reference

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19 January 2020

Luis A Lopez-Fernandez

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19 January 2020

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19 January 2020

Mariano Esteban

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Mariano Esteban

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19 January 2020

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Susana Guerra

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19 January 2020

Angel Zaballos

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13 April 2006

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19 January 2020

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Journal of Biological Chemistry

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19 January 2020

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19 January 2020

18734-18745

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19 January 2020

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The double-stranded RNA-dependent protein kinase PKR: structure and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

PKR; a sentinel kinase for cellular stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1 reference

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21 January 2018

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

1 reference

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21 January 2018

The interferon-induced double-stranded RNA-activated human p68 protein kinase inhibits the replication of vaccinia virus

1 reference

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21 January 2018

Translational control in mammalian cells

1 reference

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21 January 2018

The IRF-3 transcription factor mediates Sendai virus-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53

1 reference

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21 January 2018

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

1 reference

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21 January 2018

JNK2 and IKKbeta are required for activating the innate response to viral infection

1 reference

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21 January 2018

Vaccinia virus recombinants as a model system to analyze interferon-induced pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Activation of NF-kappa B by the dsRNA-dependent protein kinase, PKR involves the I kappa B kinase complex.

1 reference

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21 January 2018

African swine fever virus gene A179L, a viral homologue of bcl-2, protects cells from programmed cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis

1 reference

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21 January 2018

Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Cellular gene expression survey of vaccinia virus infection of human HeLa cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Microarray analysis reveals characteristic changes of host cell gene expression in response to attenuated modified vaccinia virus Ankara infection of human HeLa cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Microarray data normalization and transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The vaccinia virus E3L gene product interacts with both the regulatory and the substrate binding regions of PKR: implications for PKR autoregulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The role of the PKR-inhibitory genes, E3L and K3L, in determining vaccinia virus host range

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Features of apoptotic cells measured by flow cytometry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

A splice variant of stress response gene ATF3 counteracts NF-kappaB-dependent anti-apoptosis through inhibiting recruitment of CREB-binding protein/p300 coactivator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Antiviral actions of interferons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The protein kinase PKR: a molecular clock that sequentially activates survival and death programs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Control of alpha subunit of eukaryotic translation initiation factor 2 (eIF2 alpha) phosphorylation by the human papillomavirus type 18 E6 oncoprotein: implications for eIF2 alpha-dependent gene expression and cell death

1 reference

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21 January 2018

Proteolysis and class I major histocompatibility complex antigen presentation

1 reference

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21 January 2018

Processing and delivery of peptides presented by MHC class I molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The chaperone function of hsp70 is required for protection against stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Transcriptional repressor activating transcription factor 3 protects human umbilical vein endothelial cells from tumor necrosis factor-alpha-induced apoptosis through down-regulation of p53 transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Role for activating transcription factor 3 in stress-induced beta-cell apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Gonadotropin-releasing hormone receptor-targeted gene therapy of gynecologic cancers.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

PKR, apoptosis and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

The apoptosis pathway triggered by the interferon-induced protein kinase PKR requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Expression of transcriptional repressor ATF3/LRF1 in human atherosclerosis: colocalization and possible involvement in cell death of vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511983200

21 January 2018

Identifiers

10.1074/JBC.M511983200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16613840%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16613840%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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