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English
Nutrients and growth factors in mTORC1 activation.
scientific article published on August 2013
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
title
Nutrients and growth factors in mTORC1 activation
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
author
Alejo Efeyan
series ordinal
1
object named as
Alejo Efeyan
2 references
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
stated in
Europe PubMed Central
PMCID
3845370
retrieved
8 November 2017
David M. Sabatini
series ordinal
2
object named as
David M Sabatini
2 references
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
stated in
Europe PubMed Central
PMCID
3845370
retrieved
8 November 2017
publication date
1 August 2013
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
published in
Biochemical Society Transactions
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
volume
41
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
page(s)
902-905
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
cites work
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Amino acids and mTORC1: from lysosomes to disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
mTOR: from growth signal integration to cancer, diabetes and ageing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
mTOR and the control of whole body metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Regulation of TORC1 by Rag GTPases in nutrient response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
The role of autophagy during the early neonatal starvation period
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Identification and characterization of the tuberous sclerosis gene on chromosome 16
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
27 May 2018
Glutaminolysis activates Rag-mTORC1 signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
16 August 2018
A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
16 August 2018
Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845370
retrieved
16 August 2018
Identifiers
DOI
10.1042/BST20130063
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
Fatcat ID
release_emrxjd76ynhk3ehek52a3yee2q
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/emrxjd76ynhk3ehek52a3yee2q
retrieved
24 November 2022
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mapped directly with Wikidata item
PMCID
3845370
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
PubMed ID
23863153
1 reference
stated in
Europe PubMed Central
PMCID
3845370
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863153%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 March 2020
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