(Q43183229)

15 November 2017

title

Two pyridine derivatives as potential Cu(II) and Zn(II) chelators in therapy for Alzheimer's disease (English)

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4

Nóra V Nagy

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15 November 2017

Andrea Lakatos

1

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15 November 2017

Eva Zsigó

2

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Dominik Hollender

3

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Lívia Fülöp

5

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Dóra Simon

6

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Zsolt Bozsó

7

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Tamás Kiss

8

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15 November 2017

language of work or name

English

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publication date

27 November 2009

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15 November 2017

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volume

39

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issue

5

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15 November 2017

page(s)

1302-1315

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Alzheimer's disease is a synaptic failure

15 November 2017

cites work

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

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Copper, iron and zinc in Alzheimer's disease senile plaques.

21 January 2018

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Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis).

21 January 2018

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Metal complexing agents as therapies for Alzheimer's disease

21 January 2018

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Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

21 January 2018

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Zinc-amyloid beta interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species.

21 January 2018

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Cu(II) binding to monomeric, oligomeric, and fibrillar forms of the Alzheimer's disease amyloid-beta peptide.

21 January 2018

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Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-beta peptide

21 January 2018

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Binding of zinc(II) and copper(II) to the full-length Alzheimer's amyloid-beta peptide

21 January 2018

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Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

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Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

21 January 2018

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Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

21 January 2018

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The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice

21 January 2018

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Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis

21 January 2018

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Glycosylated tetrahydrosalens as multifunctional molecules for Alzheimer's therapy

21 January 2018

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Metal ion-dependent effects of clioquinol on the fibril growth of an amyloid {beta} peptide

21 January 2018

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Binding of Zn(II), Cu(II), and Fe(II) ions to Alzheimer's A beta peptide studied by fluorescence

21 January 2018

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The amyloid beta peptide (Abeta(1-40)) is thermodynamically soluble at physiological concentrations

21 January 2018

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The 'O-acyl isopeptide method' for the synthesis of difficult sequence-containing peptides: application to the synthesis of Alzheimer's disease-related amyloid beta peptide (Abeta) 1-42.

21 January 2018

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Aluminum-triggered structural modifications and aggregation of beta-amyloids

21 January 2018

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Vanadium (IV and V) Complexes of Reduced Schiff Bases Derived from the Reaction of Aromatico-Hydroxyaldehydes and Diamines Containing Carboxyl Groups

21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/B916366B

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15 November 2017

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