(Q43421896)

English

Long-term Aβ exposure augments mCa2+-independent mROS-mediated depletion of cardiolipin for the shift of a lethal transient mitochondrial permeability transition to its permanent mode in NARP cybrids: a protective targeting of melatonin

scientific article published in January 2013

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scholarly article

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Europe PubMed Central

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23 November 2017

Long-term Aβ exposure augments mCa2+-independent mROS-mediated depletion of cardiolipin for the shift of a lethal transient mitochondrial permeability transition to its permanent mode in NARP cybrids: a protective targeting of melatonin (English)

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Europe PubMed Central

PubMed publication ID

23 November 2017

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Russel J Reiter

4

object named as

Russel J Reiter

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Europe PubMed Central

PubMed publication ID

23 November 2017

author name string

Chia-Wei Hsiao

1

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Europe PubMed Central

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23 November 2017

Tsung-I Peng

2

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Europe PubMed Central

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23 November 2017

Alexander C Peng

3

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Europe PubMed Central

PubMed publication ID

23 November 2017

Masashi Tanaka

5

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Europe PubMed Central

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23 November 2017

Yiu-Kay Lai

6

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Europe PubMed Central

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23 November 2017

Mei-Jie Jou

7

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Europe PubMed Central

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23 November 2017

publication date

1 January 2013

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Europe PubMed Central

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23 November 2017

Journal of Pineal Research

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Europe PubMed Central

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23 November 2017

54

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Europe PubMed Central

PubMed publication ID

23 November 2017

1

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Europe PubMed Central

PubMed publication ID

23 November 2017

107-125

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Europe PubMed Central

PubMed publication ID

23 November 2017

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

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21 January 2018

Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin

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21 January 2018

Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models

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21 January 2018

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

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21 January 2018

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

1 reference

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21 January 2018

Alzheimer's disease: a lesson from mitochondrial dysfunction.

1 reference

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21 January 2018

Mitochondrial cascade hypothesis of Alzheimer's disease: myth or reality?

1 reference

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21 January 2018

Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons

1 reference

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21 January 2018

Mitochondrial dysfunction: the first domino in brain aging and Alzheimer's disease?

1 reference

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21 January 2018

Alzheimer's disease: Effects of β-amyloid on mitochondria

1 reference

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21 January 2018

Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

1 reference

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21 January 2018

Oligomeric and fibrillar species of beta-amyloid (A beta 42) both impair mitochondrial function in P301L tau transgenic mice.

1 reference

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21 January 2018

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

1 reference

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21 January 2018

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

1 reference

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21 January 2018

Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis

1 reference

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21 January 2018

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondria and Alzheimer's disease: amyloid-beta peptide uptake and degradation by the presequence protease, hPreP.

1 reference

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21 January 2018

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

1 reference

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21 January 2018

Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain

1 reference

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21 January 2018

The spirostenol (22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate blocks mitochondrial uptake of Abeta in neuronal cells and prevents Abeta-induced impairment of mitochondrial function

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

beta-Amyloid fragment 25-35 selectively decreases complex IV activity in isolated mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Energetics in the pathogenesis of neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondria: the next (neurode)generation

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondria in neuroplasticity and neurological disorders

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Neuronal calcium homeostasis and dysregulation

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Calcium signaling and amyloid toxicity in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondrial network determines intracellular ROS dynamics and sensitivity to oxidative stress through switching inter-mitochondrial messengers

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Prolonged exposure of cortical neurons to oligomeric amyloid-β impairs NMDA receptor function via NADPH oxidase-mediated ROS production: protective effect of green tea (-)-epigallocatechin-3-gallate

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Amyloid beta-peptide promotes permeability transition pore in brain mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Effect of amyloid beta-peptide on permeability transition pore: a comparative study.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Abeta(31-35) and Abeta(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: Role of the redox state of methionine-35.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Amyloid beta peptide induces cytochrome C release from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

mtDNA T8993G mutation-induced mitochondrial complex V inhibition augments cardiolipin-dependent alterations in mitochondrial dynamics during oxidative, Ca(2+), and lipid insults in NARP cybrids: a potential therapeutic target for melatonin

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Melatonin preserves the transient mitochondrial permeability transition for protection during mitochondrial Ca(2+) stress in astrocyte

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Visualization of melatonin's multiple mitochondrial levels of protection against mitochondrial Ca(2+)-mediated permeability transition and beyond in rat brain astrocytes

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondrial DNA mutations in disease and aging

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics

1 reference

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21 January 2018

Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Endogenous oxidative stress in sporadic Alzheimer's disease neuronal cybrids reduces viability by increasing apoptosis through pro-death signaling pathways and is mimicked by oxidant exposure of control cybrids

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Cybrids in Alzheimer's disease: a cellular model of the disease?

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Melatonin as a natural ally against oxidative stress: a physicochemical examination.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

1 reference

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Mitochondrial reactive oxygen species generation and calcium increase induced by visible light in astrocytes

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

In vivo measurements of respiration control by cytochrome c oxidase and in situ analysis of oxidative phosphorylation

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Calcium signaling and neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Calcium dysregulation in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Neuronal and glial calcium signaling in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Modulation of mitochondrial calcium as a pharmacological target for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Calcium and mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Ca2+ storage capacity of rat brain mitochondria declines during the postnatal development without change in ROS production capacity

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondria and heart disease

1 reference

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21 January 2018

Visualizing common deletion of mitochondrial DNA-augmented mitochondrial reactive oxygen species generation and apoptosis upon oxidative stress

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

Mitochondrial fusion and fission in mammals

1 reference

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21 January 2018

Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

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21 January 2018

Pathophysiological and pharmacological implications of mitochondria-targeted reactive oxygen species generation in astrocytes

1 reference

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21 January 2018

Respiratory active mitochondrial supercomplexes.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12004

21 January 2018

The antioxidant N-acetylcysteine prevents the mitochondrial fragmentation induced by soluble amyloid-β peptide oligomers.

1 reference

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21 January 2018

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

1 reference

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21 January 2018

Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes

1 reference

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21 January 2018

Mitochondrial ROS-induced ROS release: an update and review

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Catalytic activities of mitochondrial ATP synthase in patients with mitochondrial DNA T8993G mutation in the ATPase 6 gene encoding subunit a

1 reference

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21 January 2018

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10.1111/JPI.12004

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Europe PubMed Central

PubMed publication ID

23 November 2017

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Europe PubMed Central

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23 November 2017

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