(Q35256535)

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Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics

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scholarly article

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Europe PubMed Central

7 August 2017

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Europe PubMed Central

Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics (English)

1 reference

Europe PubMed Central

7 August 2017

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Alzheimer's disease

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author name string

Peizhong Mao

1

1 reference

Europe PubMed Central

7 August 2017

P Hemachandra Reddy

2

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Europe PubMed Central

7 August 2017

language of work or name

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publication date

18 August 2011

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Europe PubMed Central

7 August 2017

Biochimica et Biophysica Acta

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Europe PubMed Central

7 August 2017

1812

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Europe PubMed Central

7 August 2017

1359-1370

1 reference

Europe PubMed Central

7 August 2017

11

1 reference

Europe PubMed Central

7 August 2017

The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner

1 reference

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Vascular and metabolic dysfunction in Alzheimer's disease: a review

1 reference

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12 July 2018

Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation

1 reference

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Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells

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12 July 2018

DNA repair deficiency in neurodegeneration.

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12 July 2018

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

1 reference

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12 July 2018

A phase II trial of huperzine A in mild to moderate Alzheimer disease

1 reference

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12 July 2018

Amyloid β-induced impairments in hippocampal synaptic plasticity are rescued by decreasing mitochondrial superoxide

1 reference

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12 July 2018

Amyloid-Beta interaction with mitochondria

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An evolutionary review of human telomere biology: the thrifty telomere hypothesis and notes on potential adaptive paternal effects

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12 July 2018

Telomere dysfunction induces metabolic and mitochondrial compromise.

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12 July 2018

p53 governs telomere regulation feedback too, via TRF2.

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12 July 2018

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

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12 July 2018

Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

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Report of the task force on designing clinical trials in early (predementia) AD.

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Alzheimer's disease: the pros and cons of pharmaceutical, nutritional, botanical, and stimulatory therapies, with a discussion of treatment strategies from the perspective of patients and practitioners

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12 July 2018

Telomeres, lifestyle, cancer, and aging

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DNA repair in organelles: Pathways, organization, regulation, relevance in disease and aging

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12 July 2018

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

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12 July 2018

The mitochondrial transcription factor A functions in mitochondrial base excision repair

1 reference

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12 July 2018

Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease

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12 July 2018

Clinical features and pathogenesis of Alzheimer's disease: involvement of mitochondria and mitochondrial DNA.

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Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

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Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis.

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Cu(II) interaction with amyloid-beta peptide: a review of neuroactive mechanisms in AD brains

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Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?

1 reference

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Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood

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DNA repair in mammalian mitochondria: Much more than we thought?

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Neuronal and axonal loss are selectively linked to fibrillar amyloid-{beta} within plaques of the aged primate cerebral cortex

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Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons

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Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia

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The mitochondrial secret(ase) of Alzheimer's disease

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Polymorphic variation in cytochrome oxidase subunit genes

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Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline

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Neural mechanisms of ageing and cognitive decline

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Linking functional decline of telomeres, mitochondria and stem cells during ageing

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11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

1 reference

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A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration

1 reference

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Mitochondrial DNA repair and association with aging--an update

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The molecular basis of longevity, and clinical implications

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Mitochondrial mislocalization underlies Abeta42-induced neuronal dysfunction in a Drosophila model of Alzheimer's disease

1 reference

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12 July 2018

Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

1 reference

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The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

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12 July 2018

Is there a primary role of the mitochondrial genome in Alzheimer's disease?

1 reference

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12 July 2018

The role of cytochrome c oxidase deficiency in ROS and amyloid plaque formation

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12 July 2018

Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases.

1 reference

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Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice

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Role of telomere dysfunction in aging and its detection by biomarkers.

1 reference

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The non-apoptotic role of p53 in neuronal biology: enlightening the dark side of the moon

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The Alzheimer's disease mitochondrial cascade hypothesis: an update

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Bmi1 regulates mitochondrial function and the DNA damage response pathway

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12 July 2018

Role of huperzine a in the treatment of Alzheimer's disease

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Efficacy and safety of natural acetylcholinesterase inhibitor huperzine A in the treatment of Alzheimer's disease: an updated meta-analysis

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12 July 2018

DNA damage and repair in Alzheimer's disease

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Accumulated amyloid-beta peptide and hyperphosphorylated tau protein: relationship and links in Alzheimer's disease

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Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53

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Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

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Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions

1 reference

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Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

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Living on a break: cellular senescence as a DNA-damage response

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Evaluation of coenzyme Q as an antioxidant strategy for Alzheimer's disease

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Huperzine A for Alzheimer's disease

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Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

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Investigating oxidative DNA damage and its repair using the comet assay

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Mitochondrial dysfunction: the first domino in brain aging and Alzheimer's disease?

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Reactive oxygen species in mitochondria-mediated cell death

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The role of amyloid beta peptide 42 in Alzheimer's disease

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Cytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's disease

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Intracellular amyloid-beta in Alzheimer's disease

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Oxidative stress and aberrant signaling in aging and cognitive decline

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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

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The plasticity of aging: insights from long-lived mutants

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Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

A DNA damage checkpoint response in telomere-initiated senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Mitochondrial respiratory-chain diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Amyloid beta peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Human mitochondrial transcription factor A binds preferentially to oxidatively damaged DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Repair of oxidative DNA damage: mechanisms and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Free radicals in the physiological control of cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Cellular senescence as a tumor-suppressor mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Does oxidative damage to DNA increase with age?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

The comet assay: what can it really tell us?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Efficacy of tablet huperzine-A on memory, cognition, and behavior in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Purification of genomic DNA from human whole blood by isopropanol-fractionation with concentrated Nal and SDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

APP717 missense mutation affects the ratio of amyloid beta protein species (A beta 1-42/43 and a beta 1-40) in familial Alzheimer's disease brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Oxygen-derived species: their relation to human disease and environmental stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Aging, energy, and oxidative stress in neurodegenerative diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

A simple salting out procedure for extracting DNA from human nucleated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Structure and function of telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

12 July 2018

2011 Alzheimer's disease facts and figures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Caspase signalling controls microglia activation and neurotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

The emerging role of telomerase reverse transcriptase in mitochondrial DNA metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Plasma amyloid beta-42 independently predicts both late-onset depression and Alzheimer disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Alterations of plasma magnesium, copper, zinc, iron and selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: a role for peroxisomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Time-course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrome c in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Base excision repair capacity in mitochondria and nuclei: tissue-specific variations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Oxidative stress increases expression and activity of BACE in NT2 neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

The frequency of point mutations in mitochondrial DNA is elevated in the Alzheimer's brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

8-Hydroxydeoxyguanosine and 8-hydroxyguanine as biomarkers of oxidative DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Increased nuclear DNA oxidation in the brain in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

The cell division cycle and the pathophysiology of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

26 September 2018

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185172

8 December 2018

Plasma amyloid beta protein is elevated in late-onset Alzheimer disease families

1 reference

https://pubmed.ncbi.nlm.nih.gov/21871956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21871956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linking the metabolism of hydroquinone to its nephrotoxicity and nephrocarcinogenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21871956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of 8-OHdG in DNA by HPLC/ECD: the importance of DNA purity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21871956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's APP mangles mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21871956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-2 mediates neuronal cell death induced by beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/21871956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuron loss in APP transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21871956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial]

1 reference

https://pubmed.ncbi.nlm.nih.gov/21871956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comet assay for nuclear DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/21871956

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBADIS.2011.08.005

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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