(Q43567031)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

β-Secretase activity in rat astrocytes: translational block of BACE1 and modulation of BACE2 expression (English)

1 reference

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16 January 2020

0 references

2

1 reference

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16 January 2020

Alessandra Consonni

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Daniele Zacchetti

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Barbara Bettegazzi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Alessandra Di Cesare

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Romina Macco

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Ilaria Pelizzoni

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Franca Codazzi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Fabio Grohovaz

8

1 reference

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16 January 2020

language of work or name

English

0 references

publication date

14 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Neuroscience

16 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

2

1 reference

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16 January 2020

page(s)

236-243

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the down critical region

16 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

BACE1- and BACE2-expressing human cells: characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Expression analysis of BACE2 in brain and peripheral tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Translational regulation of BACE-1 expression in neuronal and non-neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Interferon gamma stimulates beta-secretase expression and sAPPbeta production in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Neuronal and nonneuronal quantitative BACE immunocytochemical expression in the entorhinohippocampal and frontal regions in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Ectodomain shedding of the amyloid precursor protein: cellular control mechanisms and novel modifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

New roles for astrocytes: redefining the functional architecture of the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Vesicle pool mobilization during action potential firing at hippocampal synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Amyloid precursor protein beta-secretase (BACE) mRNA expression in human neural cell lines following induction of neuronal differentiation and exposure to cytokines and growth factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Deciphering the molecular basis of memory failure in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Adult mouse astrocytes degrade amyloid-beta in vitro and in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

BACE2 functions as an alternative alpha-secretase in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

BACE1 expression and activity: relevance in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2010.07482.X

10.1111/J.1460-9568.2010.07482.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21073551%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference