(Q44376552)

2 December 2017

Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

amyotrophic lateral sclerosis

12 May 2020

main subject

0 references

author

Sebastien Couillard-Despres

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

5

David R Kaplan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

6

Jean-Pierre Julien

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

author name string

Minh Dang Nguyen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

Mathieu Boudreau

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

Jasna Kriz

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 March 2003

1 reference

2 December 2017

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

page(s)

2131-2140

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

12 May 2020

cites work

1 reference

12 December 2020

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

1 reference

12 December 2020

Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons.

1 reference

12 December 2020

Lack of apoptosis in mice with ALS

1 reference

12 December 2020

Upregulation of Bax protein and increased DNA degradation in ALS spinal cord motor neurons

1 reference

12 December 2020

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

1 reference

12 December 2020

Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Mitotic signaling by beta-amyloid causes neuronal death

1 reference

12 December 2020

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

12 December 2020

The retinoblastoma gene family in differentiation and development.

1 reference

12 December 2020

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

12 December 2020

E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

1 reference

12 December 2020

1 reference

12 December 2020

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

12 December 2020

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

1 reference

12 December 2020

Induction of cell-cycle regulators in simian immunodeficiency virus encephalitis

1 reference

12 December 2020

Cyclin-dependent kinases as a therapeutic target for stroke.

1 reference

12 December 2020

Alteration of the Bcl-x/Bax ratio in a transgenic mouse model of amyotrophic lateral sclerosis: evidence for the implication of the p53 signaling pathway

1 reference

12 December 2020

Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1

1 reference

12 December 2020

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment.

1 reference

12 December 2020

Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases.

1 reference

12 December 2020

Delaying caspase activation by Bcl-2: A clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

1 reference

12 December 2020

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

12 December 2020

DNA replication precedes neuronal cell death in Alzheimer's disease.

1 reference

12 December 2020

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

1 reference

12 December 2020

1 reference

12 December 2020

Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.

1 reference

12 December 2020

Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo.

1 reference

12 December 2020

Neuronal apoptosis at the G1/S cell cycle checkpoint

1 reference

12 December 2020

1 reference

12 December 2020

Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration.

1 reference

12 December 2020

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

12 December 2020

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

12 December 2020

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

12 December 2020

Cell cycle proteins exhibit altered expression patterns in lentiviral-associated encephalitis

1 reference

12 December 2020

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

12 December 2020

Innate immunity: the missing link in neuroprotection and neurodegeneration?

1 reference

12 December 2020

Hyperphosphorylation of the retinoblastoma gene product and altered subcellular distribution of E2F-1 during Alzheimer's disease and amyotrophic lateral sclerosis.

1 reference

12 December 2020

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Cycling at the interface between neurodevelopment and neurodegeneration

1 reference

12 December 2020

Altered levels and distribution of microtubule-associated proteins before disease onset in a mouse model of amyotrophic lateral sclerosis.

1 reference

12 December 2020

Superoxide dismutases

1 reference

12 December 2020

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

12 December 2020

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

1 reference

12 December 2020

Mitotic mechanisms in Alzheimer's disease?

1 reference

12 December 2020

Altered expression of bcl-2 and bax mRNA in amyotrophic lateral sclerosis spinal cord motor neurons

1 reference

12 December 2020

G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis

1 reference

12 December 2020

Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis

1 reference

12 December 2020

Neuronal Cdc2-like kinase (Nclk) binds and phosphorylates the retinoblastoma protein.

1 reference

12 December 2020

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

12 December 2020

Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimer's disease.

1 reference

12 December 2020

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

1 reference

12 December 2020

Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease.

1 reference

12 December 2020

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

1 reference

12 December 2020

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

12 December 2020

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

1 reference

12 December 2020

Cyclin-dependent kinases: engines, clocks, and microprocessors

1 reference

12 December 2020

Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

1 reference

12 December 2020

Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice

1 reference

12 December 2020

Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase

1 reference

12 December 2020

The regulation of E2F by pRB-family proteins

1 reference

12 December 2020

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

12 December 2020

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

1 reference

12 December 2020

Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase.

1 reference

12 December 2020

Immunohistochemical analysis of spinal cord lesions in amyotrophic lateral sclerosis using microtubule-associated protein 2 (MAP2) antibodies

1 reference

12 December 2020

10.1523/JNEUROSCI.23-06-02131.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741997&resulttype=core&format=json

12 May 2020

1 reference