(Q44428854)

2 December 2017

Enantioselective transport and CYP3A4-mediated metabolism of R/S-verapamil in Caco-2 cell monolayers (English)

1 reference

2 December 2017

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1 reference

Helena Engman

1

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2 December 2017

Christer Tannergren

series ordinal

2

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2 December 2017

Per Artursson

series ordinal

3

1 reference

2 December 2017

Hans Lennernäs

series ordinal

4

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2 December 2017

language of work or name

English

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publication date

1 May 2003

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European Journal of Pharmaceutical Sciences

2 December 2017

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2 December 2017

19

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2 December 2017

57-65

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2 December 2017

1

1 reference

Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein

2 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Development of Caco-2 cells expressing high levels of cDNA-derived cytochrome P4503A4.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Comparison between permeability coefficients in rat and human jejunum

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

The effect of rifampin treatment on intestinal expression of human MRP transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Transport and metabolic characterization of Caco-2 cells expressing CYP3A4 and CYP3A4 plus oxidoreductase

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Organic cation transporters in intestine, kidney, liver, and brain

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Identification of P450 enzymes involved in metabolism of verapamil in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Intestinal metabolism promotes regional differences in apical uptake of indinavir: coupled effect of P-glycoprotein and cytochrome P450 3A on indinavir membrane permeability in rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Graphical model for estimating oral bioavailability of drugs in humans and other species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Correlation of drug absorption with molecular surface properties

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Comparison of CYP3A activities in a subclone of Caco-2 cells (TC7) and human intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

The absence of stereoselective P-glycoprotein-mediated transport of R/S-verapamil across the rat jejunum

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Jejunal absorption and metabolism of R/S-verapamil in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Enantiometric separation of verapamil and norverapamil using Chiral-AGP as the stationary phase

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

The effect of ketoconazole on the jejunal permeability and CYP3A metabolism of (R/S)-verapamil in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Experimental and computational screening models for the prediction of intestinal drug absorption

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique.

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

Biopharmaceutics classification system: the scientific basis for biowaiver extensions

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900065-4

7 January 2021

10.1016/S0928-0987(03)00065-4

Identifiers

DOI

1 reference

2 December 2017

1 reference