(Q44640437)

English

Identification of Two Cyclooxygenase Active Site Residues, Leucine 384 and Glycine 526, That Control Carbon Ring Cyclization in Prostaglandin Biosynthesis

scientific article published on October 31, 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Identification of two cyclooxygenase active site residues, Leucine 384 and Glycine 526, that control carbon ring cyclization in prostaglandin biosynthesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Identification of Two Cyclooxygenase Active Site Residues, Leucine 384 and Glycine 526, That Control Carbon Ring Cyclization in Prostaglandin Biosynthesis (English)

1 reference

10.1074/JBC.M307431200

https://api.crossref.org/works/10.1074/JBC.M307431200

27 March 2024

1 reference

10.1074/JBC.M307431200

https://api.crossref.org/works/10.1074/JBC.M307431200

27 March 2024

1 reference

10.1074/JBC.M307431200

https://api.crossref.org/works/10.1074/JBC.M307431200

27 March 2024

3

object named as

A R Brash

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Claus Schneider

1

object named as

C Schneider

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

author name string

William E. Boeglin

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14594816

27 March 2024

language of work or name

0 references

publication date

31 October 2003

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

number of pages

11

1 reference

based on heuristic

inferred from page(s)

full work available at URL

http://www.jbc.org/article/S0021925820750234/pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14594816

27 March 2024

https://api.elsevier.com/content/article/PII:S0021925820750234?httpAccept=text/xml

1 reference

10.1074/JBC.M307431200

https://api.crossref.org/works/10.1074/JBC.M307431200

27 March 2024

https://api.elsevier.com/content/article/PII:S0021925820750234?httpAccept=text/plain

1 reference

10.1074/JBC.M307431200

https://api.crossref.org/works/10.1074/JBC.M307431200

27 March 2024

https://syndication.highwire.org/content/doi/10.1074/jbc.M307431200

1 reference

10.1074/JBC.M307431200

https://api.crossref.org/works/10.1074/JBC.M307431200

27 March 2024

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

4404-4414

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Arachidonic acid oxygenation by COX-1 and COX-2. Mechanisms of catalysis and inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

The cyclooxygenase reaction mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

The enzymology of prostaglandin endoperoxide H synthases-1 and -2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

The structures of prostaglandin endoperoxide H synthases-1 and -2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Identification of novel arachidonic acid metabolites formed by prostaglandin H synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Analysis of hydroperoxide-induced tyrosyl radicals and lipoxygenase activity in aspirin-treated human prostaglandin H synthase-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Synthesis of isotopically labeled arachidonic acids to probe the reaction mechanism of prostaglandin H synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

The productive conformation of arachidonic acid bound to prostaglandin synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Structural insights into the stereochemistry of the cyclooxygenase reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Prostaglandin endoperoxide H synthase-1: the functions of cyclooxygenase active site residues in the binding, positioning, and oxygenation of arachidonic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Control of prostaglandin stereochemistry at the 15-carbon by cyclooxygenases-1 and -2. A critical role for serine 530 and valine 349

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Substitution of tyrosine for the proximal histidine ligand to the heme of prostaglandin endoperoxide synthase 2: implications for the mechanism of cyclooxygenase activation and catalysis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Purification and characterization of the human recombinant histidine-tagged prostaglandin endoperoxide H synthases-1 and -2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Enantiomeric separation of hydroxy eicosanoids by chiral column chromatography: effect of the alcohol modifier.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Two distinct pathways of formation of 4-hydroxynonenal. Mechanisms of nonenzymatic transformation of the 9- and 13-hydroperoxides of linoleic acid to 4-hydroxyalkenals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Generation of 8-epiprostaglandin F2alpha by human monocytes. Discriminate production by reactive oxygen species and prostaglandin endoperoxide synthase-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Spatial requirements for 15-(R)-hydroxy-5Z,8Z,11Z, 13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2. Why acetylated COX-1 does not synthesize 15-(R)-hete

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

The binding of arachidonic acid in the cyclooxygenase active site of mouse prostaglandin endoperoxide synthase-2 (COX-2). A putative L-shaped binding conformation utilizing the top channel region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Vaccinia-T7 RNA polymerase expression system: evaluation for the expression cloning of plasma membrane transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Multiple ornithine decarboxylase forms in Physarum polycephalum: interconversion induced by cycloheximide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Eicosanoids from the tropical red alga Murrayella periclados

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Cytochrome P450-dependent transformations of 15R- and 15S-hydroperoxyeicosatetraenoic acids: stereoselective formation of epoxy alcohol products

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Autoxidation of methyl linoleate: identification of the bis-allylic 11-hydroperoxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Cyclooxygenase-dependent formation of the isoprostane, 8-epi prostaglandin F2 alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Oxygenation of 5,8,11-eicosatrienoic acid by prostaglandin endoperoxide synthase and by cytochrome P450 monooxygenase: structure and mechanism of formation of major metabolites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

Stereospecificity of hydrogen abstraction in the conversion of arachidonic acid to 15R-HETE by aspirin-treated cyclooxygenase-2. Implications for the alignment of substrate in the active site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307431200

21 January 2018

The formation of threo-11-hydroxy-trans-12: 13-epoxy-9-cis-octadecenoic acid by enzymic isomerisation of 13-L-hydroperoxy-9-cis, 11-transoctadecadienoic acid by soybean lipoxygenase-1

31

1 reference

10.1074/JBC.M307431200

https://api.crossref.org/works/10.1074/JBC.M307431200

27 March 2024

Stereochemistry of two epoxy alcohols from Saprolegnia parasitica

34

1 reference

10.1074/JBC.M307431200

https://api.crossref.org/works/10.1074/JBC.M307431200

27 March 2024

Identifiers

10.1074/JBC.M307431200

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44640437&oldid=2112569436"