(Q45048187)

http://europepmc.org/abstract/PMC/5502804

9 January 2018

title

IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity (English)

1 reference

http://europepmc.org/abstract/PMC/5502804

9 January 2018

author

Salvatore Piscuoglio

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Luciano G. Martelotto

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Charlotte K Y Ng

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Stefan Pusch

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Andreas von Deimling

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Matija Snuderl

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Sarah Chiang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Huei-Chi Wen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Fresia Pareja

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Ashwini Raghavendra

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Kathleen A Burke

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Thais Basili

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Anqi Li

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Felipe C Geyer

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jörg Balss

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Gabrielle M Baker

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Kimberly S Cole

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Julie M Batten

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jonathan D Marotti

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Hwei-Choo Soh

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Benjamin L McCalip

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jonathan Serrano

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Raymond S Lim

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Kalliopi P Siziopikou

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Song Lu

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Xiaolong Liu

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Tarek Hammour

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Edi Brogi

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

A John Iafrate

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Stuart J Schnitt

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Britta Weigelt

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Achim A Jungbluth

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jorge S Reis-Filho

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

English

0 references

publication date

20 October 2016

1 reference

http://europepmc.org/abstract/PMC/5502804

9 January 2018

published in

Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

76

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

7118-7129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

6 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5502804/fullTextXML

inferred from PubMed Central ID database lookup

cites work

IDH mutations in cancer and progress toward development of targeted therapeutics

1 reference

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Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression

25 May 2018

1 reference

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Massively Parallel Sequencing-Based Clonality Analysis of Synchronous Endometrioid Endometrial and Ovarian Carcinomas

25 May 2018

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Molecular Pathways: IDH2 Mutations-Co-opting Cellular Metabolism for Malignant Transformation

25 May 2018

1 reference

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Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

25 May 2018

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Genomic landscape of adenoid cystic carcinoma of the breast

25 May 2018

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Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification

25 May 2018

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Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.

25 May 2018

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Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

25 May 2018

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Breast cancer genomics from microarrays to massively parallel sequencing: paradigms and new insights

25 May 2018

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Mitochondrial reactive oxygen species and cancer.

25 May 2018

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TET proteins and 5-methylcytosine oxidation in hematological cancers

25 May 2018

1 reference

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IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Comprehensive analysis of DNA methylation data with RnBeads

25 May 2018

1 reference

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Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.

25 May 2018

1 reference

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Integrative genomic and transcriptomic characterization of papillary carcinomas of the breast

25 May 2018

1 reference

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Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate

25 May 2018

1 reference

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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

25 May 2018

1 reference

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Activating HER2 mutations in HER2 gene amplification negative breast cancer

25 May 2018

1 reference

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Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate

25 May 2018

1 reference

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IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives

25 May 2018

1 reference

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Comprehensive molecular portraits of human breast tumours

25 May 2018

1 reference

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IDH mutation impairs histone demethylation and results in a block to cell differentiation

25 May 2018

1 reference

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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

25 May 2018

1 reference

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25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome

25 May 2018

1 reference

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Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry

25 May 2018

1 reference

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IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Histological and molecular types of breast cancer: is there a unifying taxonomy?

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Recurring mutations found by sequencing an acute myeloid leukemia genome

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

IDH1 and IDH2 mutations in gliomas

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

An integrated genomic analysis of human glioblastoma multiforme

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Modelling glandular epithelial cancers in three-dimensional cultures

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5502804

Genetic Interactions in Cancer Progression and Treatment

25 May 2018

1 reference

12 December 2020

Immunohistochemical analyses of estrogen receptor in endometrial adenocarcinoma using a monoclonal antibody

1 reference

12 December 2020

An additional case of breast tumor resembling the tall cell variant of papillary thyroid carcinoma

1 reference

12 December 2020

Papillary carcinoma of the breast lacks evidence of RET rearrangements despite morphological similarities to papillary thyroid carcinoma

1 reference

12 December 2020

10.1158/0008-5472.CAN-16-0298

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27913435%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

27913435

1 reference