(Q45050473)

English

Elements in the N-terminal signaling sequence that determine cytosolic topology of short-chain dehydrogenases/reductases. Studies with retinol dehydrogenase type 1 and cis-retinol/androgen dehydrogenase type 1.

scientific article published on 7 September 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 December 2017

Elements in the N-terminal signaling sequence that determine cytosolic topology of short-chain dehydrogenases/reductases. Studies with retinol dehydrogenase type 1 and cis-retinol/androgen dehydrogenase type 1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

Retinol dehydrogenase 16

1 reference

GOA release 2020-03-11

author name string

Min Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

Peirong Hu

2

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

Joseph L Napoli

3

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

language of work or name

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publication date

7 September 2004

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Europe PubMed Central

PubMed publication ID

8 December 2017

number of pages

8

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based on heuristic

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

8 December 2017

279

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Europe PubMed Central

PubMed publication ID

8 December 2017

49

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

51482-51489

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

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1 reference

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Cellular retinol-binding protein I is essential for vitamin A homeostasis.

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Increased neonatal mortality in mice lacking cellular retinol-binding protein II.

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Mutations in the gene encoding 11-cis retinol dehydrogenase cause delayed dark adaptation and fundus albipunctatus

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Characterization of a dehydrogenase activity responsible for oxidation of 11-cis-retinol in the retinal pigment epithelium of mice with a disrupted RDH5 gene. A model for the human hereditary disease fundus albipunctatus

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Biosynthesis of 9-cis-retinoic acid in vivo. The roles of different retinol dehydrogenases and a structure-activity analysis of microsomal retinol dehydrogenases

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The N-terminus of retinol dehydrogenase type 1 signals cytosolic orientation in the microsomal membrane

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Identification of a mouse short-chain dehydrogenase/reductase gene, retinol dehydrogenase-similar. Function of non-catalytic amino acid residues in enzyme activity

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Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation

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21 January 2018

Calnexin: a membrane-bound chaperone of the endoplasmic reticulum

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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

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Lumenal orientation and post-translational modifications of the liver microsomal 11 beta-hydroxysteroid dehydrogenase

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21 January 2018

The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane

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21 January 2018

Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase

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Renaturation of Aequorea green-fluorescent protein

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Differential recognition of the free versus bound retinol by human microsomal retinol/sterol dehydrogenases: characterization of the holo-CRBP dehydrogenase activity of RoDH-4.

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Predicting the orientation of eukaryotic membrane-spanning proteins

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Structure and function of retinol dehydrogenases of the short chain dehydrogenase/reductase family

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21 January 2018

The role of the hydrophobic domain in orienting natural signal sequences within the ER membrane

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Molecular mechanism of signal sequence orientation in the endoplasmic reticulum

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Intracellular protein topogenesis

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The translocon: a dynamic gateway at the ER membrane

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Common principles of protein translocation across membranes

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Protein translocation: tunnel vision

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TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum.

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The signal recognition particle

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Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane

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Multiple determinants direct the orientation of signal-anchor proteins: the topogenic role of the hydrophobic signal domain

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Gene structure, expression analysis, and membrane topology of RDH4.

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Crystal structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase complexed with 17 beta-estradiol

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The Topogenic Contribution of Uncharged Amino Acids on Signal Sequence Orientation in the Endoplasmic Reticulum

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Identifiers

10.1074/JBC.M409051200

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

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