(Q45248977)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15688043%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

1 reference

title

Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation (English)

1 reference

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8 January 2020

2

1 reference

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8 January 2020

Rupert Beale

3

1 reference

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8 January 2020

author name string

Michael S Neuberger

1

1 reference

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8 January 2020

Gareth T Williams

4

1 reference

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8 January 2020

Zizhen Yang

5

1 reference

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8 January 2020

Cristina Rada

6

1 reference

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8 January 2020

publication date

1 February 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15688043%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

8 January 2020

published in

1 reference

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8 January 2020

volume

5

1 reference

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8 January 2020

page(s)

171-178

1 reference

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8 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15688043%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Amino acid sequence studies with Bence-Jones proteins

21 January 2018

1 reference

The unusual mutagenic specificity of an E. Coli mutator gene

21 January 2018

1 reference

Somatic generation of antibody diversity

21 January 2018

1 reference

Clonal selection and learning in the antibody system

21 January 2018

1 reference

The Y-family of DNA polymerases

21 January 2018

1 reference

Immunity through DNA deamination

21 January 2018

1 reference

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

21 January 2018

1 reference

DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination.

21 January 2018

1 reference

Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions

21 January 2018

1 reference

Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

21 January 2018

1 reference

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

21 January 2018

1 reference

Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line.

21 January 2018

1 reference

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

21 January 2018

1 reference

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

21 January 2018

1 reference

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

21 January 2018

1 reference

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

21 January 2018

1 reference

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

21 January 2018

1 reference

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

21 January 2018

1 reference

Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo

21 January 2018

1 reference

DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

21 January 2018

1 reference

Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas

21 January 2018

1 reference

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

21 January 2018

1 reference

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

21 January 2018

1 reference

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

21 January 2018

1 reference

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

21 January 2018

1 reference

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

21 January 2018

1 reference

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

21 January 2018

1 reference

Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

21 January 2018

1 reference

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

1 reference

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 January 2018

1 reference

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

21 January 2018

1 reference

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification

21 January 2018

1 reference

A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination

21 January 2018

1 reference

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice

21 January 2018

1 reference

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

21 January 2018

1 reference

Genesis of the strand-biased signature in somatic hypermutation of rearranged immunoglobulin variable genes

21 January 2018

1 reference

Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

21 January 2018

1 reference

Low fidelity DNA synthesis by human DNA polymerase-eta.

21 January 2018

1 reference

Error rate and specificity of human and murine DNA polymerase eta

21 January 2018

1 reference

Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.

21 January 2018

1 reference

Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene.

21 January 2018

1 reference

129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation

21 January 2018

1 reference

Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions

21 January 2018

1 reference

Origin of Endogenous DNA Abasic Sites in Saccharomyces cerevisiae

21 January 2018

1 reference

Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA

21 January 2018

1 reference

Transcription of genes encoding enzymes involved in DNA synthesis during the cell cycle of Saccharomyces cerevisiae

21 January 2018

1 reference

Maturation stage and proliferation-dependent expression of dUTPase in human T cells

21 January 2018

1 reference

The human dUTPase gene encodes both nuclear and mitochondrial isoforms. Differential expression of the isoforms and characterization of a cDNA encoding the mitochondrial species

21 January 2018

1 reference

AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

21 January 2018

1 reference

Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells

21 January 2018

1 reference

Uracil in DNA--occurrence, consequences and repair

21 January 2018

1 reference

Structure and function in the uracil-DNA glycosylase superfamily

21 January 2018

1 reference

Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication

21 January 2018

1 reference

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

21 January 2018

1 reference

Both DNA strands of antibody genes are hypermutation targets

21 January 2018

1 reference

Retroviral restriction by APOBEC proteins

21 January 2018

1 reference

Roles of uracil-DNA glycosylase and dUTPase in virus replication

21 January 2018

1 reference

Increased mutation frequency of feline immunodeficiency virus lacking functional deoxyuridine-triphosphatase

21 January 2018

1 reference

Reverse transcriptase-mediated tropism switching in Bordetella bacteriophage

21 January 2018

1 reference

A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity.

21 January 2018

1 reference

Evolution: A is for adaptation

21 January 2018

1 reference

Decreased Frequency of Somatic Hypermutation and Impaired Affinity Maturation but Intact Germinal Center Formation in Mice Expressing Antisense RNA to DNA Polymerase

21 January 2018

1 reference

Variations in Amino-Acid Sequence Near the Disulphide Bridges of Bence-Jones Proteins

21 January 2018

1 reference

Origin of Antibody Variation

21 January 2018

1 reference

Immunoglobulin Structure: Variation in the Sequence of Bence Jones Proteins

21 January 2018

1 reference

31 March 2020

Mutagenic DNA polymerase

1 reference

Probing immunoglobulin gene hypermutation with microsatellites suggests a nonreplicative short patch DNA synthesis process

31 March 2020

1 reference

Escherichia coli mutants deficient in deoxyuridine triphosphatase

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

dUTPase-minus caprine arthritis-encephalitis virus is attenuated for pathogenesis and accumulates G-to-A substitutions

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1553

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15688043%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference