(Q45288387)

11 December 2017

Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases (English)

1 reference

11 December 2017

9

1 reference

11 December 2017

Matthias P Wymann

8

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Bart Vanhaesebroeck

7

object named as

Bart Vanhaesebroeck

1 reference

11 December 2017

Matthew J Thomas

1

1 reference

11 December 2017

Alexandra Smith

2

1 reference

11 December 2017

Denise H Head

3

1 reference

11 December 2017

Laura Milne

4

1 reference

11 December 2017

Andrew Nicholls

5

1 reference

11 December 2017

Wayne Pearce

6

1 reference

11 December 2017

Alexandre Trifilieff

10

1 reference

11 December 2017

Christoph Walker

11

1 reference

11 December 2017

Peter Finan

12

1 reference

11 December 2017

John Westwick

13

1 reference

11 December 2017

language of work or name

English

0 references

publication date

1 April 2005

1 reference

European Journal of Immunology

11 December 2017

1 reference

11 December 2017

35

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11 December 2017

4

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11 December 2017

1283-1291

1 reference

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

11 December 2017

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

Interactions between neutrophils and cytokines in blood and alveolar spaces during ARDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by Fc epsilon R1 cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

Optimal chemotactic responses of leukemic T cells to stromal cell-derived factor-1 requires the activation of both class IA and IB phosphoinositide 3-kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

Synthesis and function of 3-phosphorylated inositol lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Phosphoinositide 3-kinase signalling--which way to target?

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Effects of wortmannin on airways inflammation induced by allergen in actively sensitised Brown Norway rats

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Membrane targeting by pleckstrin homology domains.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Gene-targeting reveals physiological roles and complex regulation of the phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Resistance to thromboembolism in PI3Kgamma-deficient mice.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Chronic obstructive pulmonary disease * 12: New treatments for COPD

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Relationship between interleukin 1 (IL1), tumor necrosis factor (TNF) and a neutrophil attracting peptide (NAP-1).

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Identification of three related human GRO genes encoding cytokine functions

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Requirement for PI 3-kinase gamma in macrophage migration to MCP-1 and CSF-1.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Selective role of PI3K delta in neutrophil inflammatory responses

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Turning on the respiratory burst

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

A role for phosphoinositide 3--kinase in RANTES induced chemotaxis of T lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Chemoattractant receptor-stimulated F-actin polymerization in the human neutrophil is signaled by 2 distinct pathways

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200425634

7 January 2021

Identifiers

DOI

10.1002/EJI.200425634

1 reference

11 December 2017

1 reference