(Q45305431)

11 December 2017

Detection of polyglutamine protein oligomers in cells by fluorescence correlation spectroscopy (English)

1 reference

11 December 2017

Yasuo Takahashi

1

1 reference

11 December 2017

Yuma Okamoto

2

1 reference

11 December 2017

H Akiko Popiel

3

1 reference

11 December 2017

Nobuhiro Fujikake

4

1 reference

11 December 2017

Tatsushi Toda

5

1 reference

11 December 2017

Masataka Kinjo

6

1 reference

11 December 2017

Yoshitaka Nagai

7

1 reference

11 December 2017

language of work or name

English

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publication date

15 June 2007

1 reference

Journal of Biological Chemistry

11 December 2017

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11 December 2017

282

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11 December 2017

33

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11 December 2017

24039-24048

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Toxic proteins in neurodegenerative disease

11 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Opinion: What is the role of protein aggregation in neurodegeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

21 January 2018

Conformational disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Glutamine repeats and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Aggresomes, inclusion bodies and protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Sorting single molecules: application to diagnostics and evolutionary biotechnology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Fluorescence correlation spectroscopy measures molecular transport in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Oligomeric tubulin in large transporting complex is transported via kinesin in squid giant axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Diffusion-time distribution analysis reveals characteristic ligand-dependent interaction patterns of nuclear receptors in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Interaction of a small heat shock protein of the fission yeast, Schizosaccharomyces pombe, with a denatured protein at elevated temperature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Analysis of cellular functions by multipoint fluorescence correlation spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Using GFP in FRET-based applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Studying protein dynamics in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Protein transduction domain-mediated delivery of QBP1 suppresses polyglutamine-induced neurodegeneration in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Amino Acid Sequence Requirements of Peptides That Inhibit Polyglutamine-Protein Aggregation and Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Fluorescence correlation spectroscopy and quantitative cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

Systemic administration of Congo red does not improve motor or cognitive function in R6/2 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704789200

21 January 2018

Identifiers

DOI

10.1074/JBC.M704789200

1 reference

11 December 2017

1 reference