(Q45947707)

20 February 2018

title

Elucidation of amyloid beta-protein oligomerization mechanisms: discrete molecular dynamics study. (English)

1 reference

20 February 2018

author name string

B Urbanc

1

1 reference

20 February 2018

M Betnel

2

1 reference

20 February 2018

L Cruz

3

1 reference

20 February 2018

G Bitan

4

1 reference

20 February 2018

D B Teplow

5

1 reference

20 February 2018

language of work or name

English

0 references

publication date

1 March 2010

1 reference

20 February 2018

Journal of the American Chemical Society

published in

1 reference

20 February 2018

volume

132

1 reference

20 February 2018

issue

12

1 reference

20 February 2018

page(s)

4266-4280

1 reference

20 February 2018

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

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Role of electrostatic interactions in amyloid beta-protein (A beta) oligomer formation: a discrete molecular dynamics study

24 May 2018

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24 May 2018

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Structural study of metastable amyloidogenic protein oligomers by photo-induced cross-linking of unmodified proteins

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24 May 2018

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A specific amyloid-beta protein assembly in the brain impairs memory

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Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

24 May 2018

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Solvent and mutation effects on the nucleation of amyloid beta-protein folding

24 May 2018

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24 May 2018

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On the nucleation of amyloid beta-protein monomer folding

24 May 2018

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Folding events in the 21-30 region of amyloid beta-protein (Abeta) studied in silico

24 May 2018

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Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

24 May 2018

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In silico study of amyloid beta-protein folding and oligomerization

24 May 2018

1 reference

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Folding Trp-cage to NMR resolution native structure using a coarse-grained protein model

24 May 2018

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Molecular dynamics simulation of amyloid beta dimer formation

24 May 2018

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24 May 2018

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Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration

24 May 2018

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Mechanism for the alpha-helix to beta-hairpin transition

24 May 2018

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Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

24 May 2018

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Solution structure of the Alzheimer amyloid beta-peptide (1-42) in an apolar microenvironment. Similarity with a virus fusion domain

24 May 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

24 May 2018

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Structure determination of micelle-like intermediates in amyloid beta -protein fibril assembly by using small angle neutron scattering

24 May 2018

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The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

24 May 2018

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Probing the origins of increased activity of the E22Q "Dutch" mutant Alzheimer's beta-amyloid peptide

24 May 2018

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alpha-helix formation: discontinuous molecular dynamics on an intermediate-resolution protein model

24 May 2018

1 reference

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Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins

24 May 2018

1 reference

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The Alzheimer's peptide a beta adopts a collapsed coil structure in water

24 May 2018

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24 May 2018

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Discrete molecular dynamics studies of the folding of a protein-like model.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Folding thermodynamics of a model three-helix-bundle protein.

24 May 2018

1 reference

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24 May 2018

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24 May 2018

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A simple method for displaying the hydropathic character of a protein

24 May 2018

1 reference

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Identifying the protein folding nucleus using molecular dynamics.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Effects of the Arctic (E22-->G) mutation on amyloid beta-protein folding: discrete molecular dynamics study

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Characterizations of distinct amyloidogenic conformations of the Abeta (1-40) and (1-42) peptides.

15 August 2018

1 reference

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Abeta42 is more rigid than Abeta40 at the C terminus: implications for Abeta aggregation and toxicity.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Formation and stabilization model of the 42-mer Abeta radical: implications for the long-lasting oxidative stress in Alzheimer's disease

15 August 2018

1 reference

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A molecular switch in amyloid assembly: Met35 and amyloid beta-protein oligomerization

15 August 2018

1 reference

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Alzheimer's disease: genetic evidence points to a single pathogenesis.

15 August 2018

1 reference

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Elucidation of primary structure elements controlling early amyloid beta-protein oligomerization.

15 August 2018

1 reference

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Kinetic studies of amyloid beta-protein fibril assembly. Differential effects of alpha-helix stabilization

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Protein refolding versus aggregation: computer simulations on an intermediate-resolution protein model

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Assembly of a tetrameric alpha-helical bundle: computer simulations on an intermediate-resolution protein model

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Folding of a model three-helix bundle protein: a thermodynamic and kinetic analysis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5767167

First-Order Disorder-to-Order Transition in an Isolated Homopolymer Model

3 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20218566

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JA9096303

1 reference

20 February 2018

PMC publication ID

5767167

1 reference

20 February 2018

PubMed publication ID

20218566

1 reference

20 February 2018