(Q45969433)

18 December 2017

title

Molecular and neurochemical mechanisms in PD pathogenesis. (English)

1 reference

18 December 2017

author

Irmgard Paris

1

1 reference

18 December 2017

Juan Segura-Aguilar

5

1 reference

18 December 2017

Carolina Perez-Pastene

3

object named as

Carolina Perez-Pastene

1 reference

18 December 2017

author name string

Jorge Lozano

2

1 reference

18 December 2017

Patricia Muñoz

4

1 reference

18 December 2017

publication date

20 May 2009

1 reference

18 December 2017

published in

Neurotoxicity Research

1 reference

18 December 2017

volume

16

1 reference

18 December 2017

issue

3

1 reference

18 December 2017

page(s)

271-279

1 reference

18 December 2017

https://scigraph.springernature.com/pub.10.1007/s12640-009-9059-4

exact match

0 references

cites work

Methionine oxidation, alpha-synuclein and Parkinson's disease

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12640-009-9059-4

Alpha-synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells

21 January 2018

1 reference

12 December 2020

Copper neurotoxicity in rat substantia nigra and striatum is dependent on DT-diaphorase inhibition

1 reference

12 December 2020

MPP(+)-induced degeneration is potentiated by dicoumarol in cultures of the RCSN-3 dopaminergic cell line. Implications of neuromelanin in oxidative metabolism of dopamine neurotoxicity

1 reference

12 December 2020

Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein.

1 reference

12 December 2020

Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

1 reference

12 December 2020

The possible role of one-electron reduction of aminochrome in the neurodegenerative process of the dopaminergic system.

1 reference

12 December 2020

Inhibition of VMAT-2 and DT-diaphorase induce cell death in a substantia nigra-derived cell line--an experimental cell model for dopamine toxicity studies

1 reference

12 December 2020

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

1 reference

12 December 2020

The 6-hydroxydopamine model of Parkinson's disease

1 reference

12 December 2020

Nuclear and neuritic distribution of serine-129 phosphorylated alpha-synuclein in transgenic mice

1 reference

12 December 2020

Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease

1 reference

12 December 2020

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

1 reference

12 December 2020

Dopamine-dependent iron toxicity in cells derived from rat hypothalamus

1 reference

12 December 2020

Accumulation of phosphorylated alpha-synuclein in dopaminergic neurons of transgenic mice that express human alpha-synuclein

1 reference

12 December 2020

Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity

1 reference

12 December 2020

Catecholamines oxidation by xanthine oxidase

1 reference

12 December 2020

Dopamine Affects the Stability, Hydration, and Packing of Protofibrils and Fibrils of the Wild Type and Variants of α-Synuclein†

1 reference

12 December 2020

Alpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recycling

1 reference

12 December 2020

Behavioral effects of manganese injected in the rat substantia nigra are potentiated by dicumarol, a DT-diaphorase inhibitor

1 reference

12 December 2020

Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells.

1 reference

12 December 2020

The biochemical basis of Parkinson's disease: the role of catecholamine o-quinones: a review-discussion

1 reference

12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

12 December 2020

On the mechanism of the Mn3(+)-induced neurotoxicity of dopamine:prevention of quinone-derived oxygen toxicity by DT diaphorase and superoxide dismutase

1 reference

12 December 2020

Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates.

1 reference

12 December 2020

Alpha-synuclein and Parkinson's disease: Implications from the screening of more than 1,900 patients

1 reference

12 December 2020

A role for alpha-synuclein in the regulation of dopamine biosynthesis

1 reference

12 December 2020

The association of alpha-synuclein with membranes affects bilayer structure, stability, and fibril formation

1 reference

12 December 2020

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

1 reference

12 December 2020

Superoxide dismutase and catalase enhance autoxidation during one-electron reduction of aminochrome by NADPH-cytochrome P-450 reductase

1 reference

12 December 2020

Alpha-synuclein A30P point-mutation generates age-dependent nigrostriatal deficiency in mice

1 reference

12 December 2020

A cell-based model of alpha-synucleinopathy for screening compounds with therapeutic potential of Parkinson's disease

1 reference

12 December 2020

Nitration inhibits fibrillation of human α‐synuclein in vitro by formation of soluble oligomers

1 reference

12 December 2020

Dopamine covalently modifies and functionally inactivates parkin

1 reference

12 December 2020

Monoamine transporter inhibitors and norepinephrine reduce dopamine-dependent iron toxicity in cells derived from the substantia nigra

1 reference

12 December 2020

Role of individual methionines in the fibrillation of methionine-oxidized alpha-synuclein

1 reference

12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

12 December 2020

Copper neurotoxicity is dependent on dopamine-mediated copper uptake and one-electron reduction of aminochrome in a rat substantia nigra neuronal cell line

1 reference

12 December 2020

Inhibition of DT-diaphorase is a requirement for Mn(III) to produce a 6-OH-dopamine like rotational behaviour

1 reference

12 December 2020

The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease

1 reference

12 December 2020

Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter.

1 reference

12 December 2020

The catecholaminergic RCSN-3 cell line: a model to study dopamine metabolism

1 reference

12 December 2020

Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein

1 reference

12 December 2020

Enzymatic dopamine peroxidation in substantia nigra of human brain

1 reference

12 December 2020

Alpha-synuclein alters proteasome function, protein synthesis, and stationary phase viability.

1 reference

12 December 2020

Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice.

1 reference

12 December 2020

Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology

1 reference

12 December 2020

Alpha-synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: lessons from viral transduction of knockout mice

1 reference

12 December 2020

Selective noradrenergic vulnerability in α-synuclein transgenic mice

1 reference

12 December 2020

Alpha-synuclein misfolding and neurodegenerative diseases

1 reference

12 December 2020

Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice

1 reference

12 December 2020

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

12 December 2020

Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein

1 reference

12 December 2020

Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase.

1 reference

12 December 2020

1 reference

12 December 2020

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

1 reference

12 December 2020

Exploring neurocircuitries of the basal ganglia by intracerebral administration of selective neurotoxins

1 reference

12 December 2020

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

12 December 2020

Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze?

1 reference

12 December 2020

Peroxidase activity of liver microsomal vitamin D 25-hydroxylase and cytochrome P450 1A2 catalyzes 25-hydroxylation of vitamin D3 and oxidation of dopamine to aminochrome

1 reference

12 December 2020

Neurotoxins and neurotoxicity mechanisms. An overview.

1 reference

12 December 2020

Model fusion, the next phase in developing animal models for Parkinson's disease

1 reference

12 December 2020

Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis

1 reference

12 December 2020

Cellular oligomerization of alpha-synuclein is determined by the interaction of oxidized catechols with a C-terminal sequence

1 reference

12 December 2020

Enzymatic oxidation of dopamine: the role of prostaglandin H synthase

1 reference

12 December 2020

Certain Metals Trigger Fibrillation of Methionine-oxidized α-Synuclein

1 reference

12 December 2020

Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

1 reference

12 December 2020

Alpha-synuclein in Lewy bodies

1 reference

12 December 2020

On the neurotoxicity mechanism of leukoaminochrome o-semiquinone radical derived from dopamine oxidation: mitochondria damage, necrosis, and hydroxyl radical formation

1 reference

12 December 2020

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

1 reference

12 December 2020

Aminochrome as a preclinical experimental model to study degeneration of dopaminergic neurons in Parkinson's disease

1 reference

12 December 2020

Distribution of DT diaphorase in the rat brain: biochemical and immunohistochemical studies

1 reference

12 December 2020

Concerted action of metals and macromolecular crowding on the fibrillation of alpha-synuclein

1 reference

12 December 2020

Metabolic activation of dopamine o-quinones to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects

1 reference

12 December 2020

The neurotoxin, MPP+, induces hyperphosphorylation of Tau, in the presence of alpha-Synuclein, in SH-SY5Y neuroblastoma cells

1 reference

12 December 2020

Alpha-synuclein induces hyperphosphorylation of Tau in the MPTP model of parkinsonism

1 reference

12 December 2020

Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors

1 reference

12 December 2020

Beta-synuclein inhibits formation of alpha-synuclein protofibrils: a possible therapeutic strategy against Parkinson's disease

1 reference

12 December 2020

Inhibition of DT-diaphorase potentiates the in vivo neurotoxic effect of intranigral injection of salsolinol in rats.

1 reference

12 December 2020

Inhibition of alpha-synuclein fibrillization by dopamine analogs via reaction with the amino groups of alpha-synuclein. Implication for dopaminergic neurodegeneration

1 reference

12 December 2020

Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.

1 reference

12 December 2020

Recombinant cytochrome P450 2D18 metabolism of dopamine and arachidonic acid

1 reference

12 December 2020

Behavioral effects of aminochrome and dopachrome injected in the rat substantia nigra.

1 reference

12 December 2020

Covalent arylation of metallothionein by oxidized dopamine products: a possible mechanism for zinc-mediated enhancement of dopaminergic neuron survival

1 reference

12 December 2020

Dopamine oxidation generates an oxidative stress mediated by dopamine semiquinone and unrelated to reactive oxygen species

1 reference

12 December 2020

Synuclein activates microglia in a model of Parkinson's disease

1 reference

12 December 2020

Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations.

1 reference

12 December 2020

10.1007/S12640-009-9059-4

Identifiers

DOI

1 reference

18 December 2017

Dimensions Publication ID

1046186035

0 references

1 reference

18 December 2017