(Q46164744)

20 December 2017

title

Single-molecule assays for investigating protein misfolding and aggregation (English)

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20 December 2017

author name string

Armin Hoffmann

series ordinal

1

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20 December 2017

Krishna Neupane

series ordinal

2

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20 December 2017

Michael T Woodside

series ordinal

3

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20 December 2017

language of work or name

English

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publication date

23 April 2013

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20 December 2017

Physical Chemistry Chemical Physics

published in

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20 December 2017

volume

15

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20 December 2017

issue

21

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20 December 2017

page(s)

7934-7948

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20 December 2017

Principles of protein folding, misfolding and aggregation

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Folding and association versus misfolding and aggregation of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Prevention of amyloid-like aggregation as a driving force of protein evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

21 January 2018

Co-translational folding

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Molecular chaperones in protein folding and proteostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Cellular strategies for controlling protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protein drug stability: a formulation challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protein aggregation and its inhibition in biopharmaceutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Insulin analogues and their potential in the management of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Structure of the cross-beta spine of amyloid-like fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protein misfolding, functional amyloid, and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Structural classification of toxic amyloid oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Functional amyloid--from bacteria to humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

A diversity of assembly mechanisms of a generic amyloid fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Quantitative and spatio-temporal features of protein aggregation in Escherichia coli and consequences on protein quality control and cellular ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The propagation of prion-like protein inclusions in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Transmission of prions within the gut and towards the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The transcellular spread of cytosolic amyloids, prions, and prionoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Intermolecular transmission of superoxide dismutase 1 misfolding in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Purified and synthetic Alzheimer's amyloid beta (Aβ) prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Non-native protein aggregation kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protein aggregation kinetics, mechanism, and curve-fitting: a review of the literature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Polymorphism in the intermediates and products of amyloid assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

For protein misassembly, it's the "I" decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The presence of valine at residue 129 in human prion protein accelerates amyloid formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Phosphorylation as a tool to modulate aggregation propensity and to predict fibril architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The osmophobic effect: natural selection of a thermodynamic force in protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Molecular level insight into intra-solvent interaction effects on protein stability and aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Experimental investigation of protein folding and misfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Techniques to study amyloid fibril formation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Assays for α-synuclein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Techniques for Monitoring Protein Misfolding and Aggregation in Vitro and in Living Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single-molecule studies of protein folding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protein folding at single-molecule resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Illuminating single molecules in condensed matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Fluorescence spectroscopy of single molecules under ambient conditions: methodology and technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

A practical guide to single-molecule FRET

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The physics of life: one molecule at a time

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Surfaces and orientations: much to FRET about?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Suppressing Brownian motion of individual biomolecules in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Development of a technique for the investigation of folding dynamics of single proteins for extended time periods

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Recent advances in single-molecule detection on micro- and nano-fluidic devices

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protein folding studied by single-molecule FRET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Function and dysfunction of α-synuclein: probing conformational changes and aggregation by single molecule fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single-molecule approaches to prion protein misfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Fluorescence correlation spectroscopy: novel variations of an established technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Rapid acquisition of beta-sheet structure in the prion protein prior to multimer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Amyloid beta-peptide polymerization studied using fluorescence correlation spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The amyloid beta peptide (Abeta(1-40)) is thermodynamically soluble at physiological concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Measuring Size Distribution in Highly Heterogeneous Systems with Fluorescence Correlation Spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Measurement of the attachment and assembly of small amyloid-β oligomers on live cell membranes at physiological concentrations using single-molecule tools.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Early aggregation steps in alpha-synuclein as measured by FCS and FRET: evidence for a contagious conformational change.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Art and artefacts of fluorescence correlation spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Resolution of fluorescence correlation measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Two-focus fluorescence correlation spectroscopy: a new tool for accurate and absolute diffusion measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Detection of prion particles in samples of BSE and scrapie by fluorescence correlation spectroscopy without proteinase K digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single particle analysis of manganese-induced prion protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Converse modulation of toxic alpha-synuclein oligomers in living cells by N'-benzylidene-benzohydrazide derivates and ferric iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Direct characterization of amyloidogenic oligomers by single-molecule fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β(1-40) peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single molecule characterization of α-synuclein in aggregation-prone states

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Alteration of the alpha-synuclein folding landscape by a mutation related to Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Direct observation of the interconversion of normal and toxic forms of α-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Monitoring the earliest amyloid-beta oligomers via quantized photobleaching of dye-labeled peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Determination of the oligomer size of amyloidogenic protein beta-amyloid(1-40) by single-molecule spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protein unfolding and refolding under force: methodologies for nanomechanics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

High-resolution, single-molecule measurements of biomolecular motion

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Theory, analysis, and interpretation of single-molecule force spectroscopy experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Passive all-optical force clamp for high-resolution laser trapping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Force-clamp spectroscopy monitors the folding trajectory of a single protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Full distance-resolved folding energy landscape of one single protein molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Energy landscape analysis of native folding of the prion protein yields the diffusion constant, transition path time, and rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The folding cooperativity of a protein is controlled by its chain topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Observing folding pathways and kinetics of a single sodium-proton antiporter from Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Conformational equilibria in monomeric alpha-synuclein at the single-molecule level

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The complex folding network of single calmodulin molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single-molecule observation of helix staggering, sliding, and coiled coil misfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Direct observation of multiple misfolding pathways in a single prion protein molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Signal-pair correlation analysis of single-molecule trajectories.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

alpha-Synuclein misfolding: single molecule AFM force spectroscopy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Effect of spermidine on misfolding and interactions of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single-molecule atomic force microscopy force spectroscopy study of Aβ-40 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Effect of electrostatics on aggregation of prion protein Sup35 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Dynamic strength of molecular adhesion bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Tandem repeating modular proteins avoid aggregation in single molecule force spectroscopy experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Spectrin domains lose cooperativity in forced unfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Tracking UNC-45 chaperone-myosin interaction with a titin mechanical reporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Protein folding drives disulfide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Direct observation of chaperone-induced changes in a protein folding pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

In vitro and in vivo neurotoxicity of prion protein oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Nanomechanical properties of single amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Nanomechanical properties of human prion protein amyloid as probed by force spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Mechanical manipulation of Alzheimer's amyloid beta1-42 fibrils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Optical trapping with high forces reveals unexpected behaviors of prion fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Physical properties of polymorphic yeast prion amyloid fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Nanomaterials: amyloids reflect their brighter side

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Nanopore analysis: An emerging technique for studying the folding and misfolding of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

21 January 2018

Solid-state nanopores

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Nanopore analysis of β-amyloid peptide aggregation transition induced by small molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Controlling protein translocation through nanopores with bio-inspired fluid walls.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single-particle characterization of Aβ oligomers in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Microsecond folding experiments and simulations: a match is made

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

The conformational ensembles of α-synuclein and tau: combining single-molecule FRET and simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Single particle detection of Aβ aggregates associated with Alzheimer’s disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

AFM-based force spectroscopy measurements of mature amyloid fibrils of the peptide glucagon

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Information Content in Fluorescence Correlation Spectroscopy: Binary Mixtures and Detection Volume Distortion

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

Horizontal prion transmission in mule deer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3CP44564J

21 January 2018

Identifiers

DOI

10.1039/C3CP44564J

1 reference

20 December 2017

1 reference

20 December 2017