(Q46367140)

21 December 2017

title

GSTpi expression in MPTP-induced dopaminergic neurodegeneration of C57BL/6 mouse midbrain and striatum (English)

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21 December 2017

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Isabel Peixeiro

3

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Andreia Neves Carvalho

Andreia Neves Carvalho

2

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Margarida Castro-Caldas

Margarida Castro-Caldas

1

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Maria João Gama

Maria João Gama

6

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Elsa Rodrigues

Elsa Rodrigues

4

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author name string

Maria Celeste Lechner

5

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21 December 2017

publication date

16 September 2008

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21 December 2017

Journal of Molecular Neuroscience

published in

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21 December 2017

volume

38

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21 December 2017

issue

2

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21 December 2017

page(s)

114-127

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21 December 2017

https://scigraph.springernature.com/pub.10.1007/s12031-008-9141-z

exact match

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cites work

Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes

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Crossref

https://api.crossref.org/works/10.1007%2FS12031-008-9141-Z

Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS12031-008-9141-Z

An important role of Nrf2-ARE pathway in the cellular defense mechanism

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS12031-008-9141-Z

Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo

21 January 2018

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12 December 2020

Distribution of mitochondrial manganese superoxide dismutase among rat glial cells in culture.

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12 December 2020

Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases

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12 December 2020

Developmental changes in the cellular distribution of glutathione and glutathione S-transferases in the murine nervous system.

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12 December 2020

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

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12 December 2020

Oxidative stress and genetics in the pathogenesis of Parkinson's disease

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12 December 2020

Pathogenic role of glial cells in Parkinson's disease.

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12 December 2020

Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi

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12 December 2020

Glia cell number modulates sensitivity to MPTP in mice

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12 December 2020

GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism

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12 December 2020

Different vulnerability to cytotoxicity and susceptibility to protection of progenitors versus mature oligodendrocytes.

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12 December 2020

Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

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12 December 2020

Molecular mechanisms of enhanced susceptibility to apoptosis in differentiating oligodendrocytes.

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12 December 2020

Inflammation and neurodegeneration in Parkinson's disease

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12 December 2020

Glia: a curtain raiser

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12 December 2020

Peroxide-scavenging deficit underlies oligodendrocyte susceptibility to oxidative stress

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12 December 2020

Glutathione S-transferase polymorphisms and onset age in alpha-synuclein A53T mutant Parkinson's disease.

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12 December 2020

Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

1 reference

12 December 2020

Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson's disease mice model

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12 December 2020

Preventive effect of antioxidants in MPTP-induced mouse model of Parkinson's disease

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12 December 2020

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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12 December 2020

Glutathione transferases--structure and catalytic activity

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12 December 2020

Apoptotic molecules and MPTP-induced cell death

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12 December 2020

Glial cell participation in the degeneration of dopaminergic neurons in Parkinson's disease

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12 December 2020

The mouse MPTP model: gene expression changes in dopaminergic neurons

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12 December 2020

Acute ultrastructural effects of MPTP on the nigrostriatal pathway of the C57BL/6 adult mouse: evidence of compensatory plasticity in nigrostriatal neurons

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12 December 2020

A Pi Form of Glutathione-S-Transferase Is a Myelin-and Oligodendrocyte-Associated Enzyme in Mouse Brain

1 reference

12 December 2020

Biochemical pathophysiology of Parkinson's disease.

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12 December 2020

Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

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12 December 2020

Glial reactions in Parkinson's disease

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12 December 2020

Mitochondria, oxidative damage, and inflammation in Parkinson's disease

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12 December 2020

Glutathione transferases

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12 December 2020

Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors.

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12 December 2020

Depletion of glutathione interferes with induction of glycerolphosphate dehydrogenase in the brains of young rats

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12 December 2020

Long-lasting reactive changes observed in microglia in the striatal and substantia nigral of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

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12 December 2020

Disease model: Parkinson's disease.

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12 December 2020

Parkinson's disease, pesticides, and glutathione transferase polymorphisms

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12 December 2020

Absolute requirement of GDNF for adult catecholaminergic neuron survival

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12 December 2020

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1

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12 December 2020

Method for culturing postnatal substantia nigra as an in vitro model of experimental Parkinson's disease

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12 December 2020

Regulation of JNK signaling by GSTp

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12 December 2020

Human glutathione S-transferases

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12 December 2020

Neuromelanin and iron in human locus coeruleus and substantia nigra during aging: consequences for neuronal vulnerability.

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12 December 2020

Intracellular translocation of glutathione S-transferase pi during oligodendrocyte differentiation in adult rat cerebral cortex in vivo

1 reference

12 December 2020

Dual effects of antioxidants in neurodegeneration: direct neuroprotection against oxidative stress and indirect protection via suppression of glia-mediated inflammation

1 reference

12 December 2020

Oxidative stress in Parkinson's disease

1 reference

12 December 2020

Glutathione pathways in the brain.

1 reference

12 December 2020

MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo

1 reference

12 December 2020

P450 and heme oxygenase enzymes in the basal ganglia and their roles in Parkinson's disease

1 reference

12 December 2020

Neurochemical findings in the MPTP model of Parkinson's disease

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12 December 2020

Association of A313 G polymorphism (GSTP1*B) in the glutathione-S-transferase P1 gene with sporadic Parkinson's disease.

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12 December 2020

Parkinson's disease--a multifactorial neurodegenerative disorder.

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12 December 2020

Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes

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12 December 2020

Expression of bcl-2 inhibits necrotic neural cell death.

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12 December 2020

Glutathione S-transferase isoenzymatic response to aging in rat cerebral cortex and cerebellum.

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12 December 2020

Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome

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12 December 2020

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

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12 December 2020

Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease

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12 December 2020

Glutathione S-transferase Pi is a dopamine-inducible suppressor of dopamine-induced apoptosis in PC12 cells

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12 December 2020

Nomenclature for mammalian soluble glutathione transferases

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12 December 2020

Glutathione S-transferase polymorphisms and their biological consequences

1 reference

12 December 2020

MPTP as a mitochondrial neurotoxic model of Parkinson's disease

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12 December 2020

GST function in drug and stress response

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12 December 2020

Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism

1 reference

12 December 2020

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

1 reference

12 December 2020

Evidence for generation of oxidative stress in brain by MPTP: in vitro and in vivo studies in mice.

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12 December 2020

Parkinson's disease: mechanisms and models

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12 December 2020

10.1007/S12031-008-9141-Z

Identifiers

DOI

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21 December 2017

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21 December 2017