(Q46726131)

24 December 2017

http://europepmc.org/abstract/MED/25994759

title

Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence (English)

1 reference

24 December 2017

http://europepmc.org/abstract/MED/25994759

main subject

head and neck squamous cell carcinoma

0 references

author

Curtis R Pickering

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Sang Hyeok Woo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Liang P Yang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Hui-Ching Chuang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Alison Fitzgerald

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Ho-Young Lee

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Jeffrey N Myers

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Heath D Skinner

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

publication date

20 May 2015

1 reference

24 December 2017

http://europepmc.org/abstract/MED/25994759

published in

Head & Neck

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

38 Suppl 1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

E934-40

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

Senescence in tumours: evidence from mice and humans

12 June 2020

cites work

1 reference

Pro-senescence therapy for cancer treatment

21 January 2018

1 reference

Therapy-induced senescence in cancer

21 January 2018

1 reference

5-aza-2'-deoxycytidine-mediated c-myc Down-regulation triggers telomere-dependent senescence by regulating human telomerase reverse transcriptase in chronic myeloid leukemia

21 January 2018

1 reference

TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.

21 January 2018

1 reference

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence

21 January 2018

1 reference

Regulation of cancer cell metabolism

21 January 2018

1 reference

Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion

21 January 2018

1 reference

Identification of ROS using oxidized DCFDA and flow-cytometry.

21 January 2018

1 reference

Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation

21 January 2018

1 reference

Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

21 January 2018

1 reference

Four faces of cellular senescence.

21 January 2018

1 reference

Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53.

21 January 2018

1 reference

Feedback between p21 and reactive oxygen production is necessary for cell senescence

21 January 2018

1 reference

Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2

21 January 2018

1 reference

Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling.

21 January 2018

1 reference

Senescence and aging: the critical roles of p53.

21 January 2018

1 reference

The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells

21 January 2018

1 reference

p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint

21 January 2018

1 reference

The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms.

21 January 2018

1 reference

4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway

21 January 2018

1 reference

p53 and p16(INK4A) independent induction of senescence by chromatin-dependent alteration of S-phase progression

21 January 2018

1 reference

The essence of senescence

21 January 2018

1 reference

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/HED.24129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25994759%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference