(Q38082328)

28 August 2017

title

Senescence and aging: the critical roles of p53. (English)

1 reference

28 August 2017

A Rufini

1

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28 August 2017

P Tucci

series ordinal

2

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28 August 2017

I Celardo

series ordinal

3

1 reference

28 August 2017

G Melino

series ordinal

4

1 reference

28 August 2017

language of work or name

English

0 references

publication date

18 February 2013

1 reference

28 August 2017

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28 August 2017

volume

32

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28 August 2017

issue

43

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28 August 2017

page(s)

5129-5143

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Defining cellular senescence in IMR-90 cells: a flow cytometric analysis

28 August 2017

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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The ataxia telangiectasia-mutated target site Ser18 is required for p53-mediated tumor suppression

31 March 2020

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Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX.

31 March 2020

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31 March 2020

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31 March 2020

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Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes

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31 March 2020

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31 March 2020

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Blinded by the Light: The Growing Complexity of p53

31 March 2020

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E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repression

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila

31 March 2020

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A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways

31 March 2020

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PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation

31 March 2020

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Weak p53 permits senescence during cell cycle arrest

31 March 2020

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Autophagy: from phenomenology to molecular understanding in less than a decade

31 March 2020

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31 March 2020

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Role of autophagy in disease resistance and hypersensitive response-associated cell death

31 March 2020

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The autophagic paradox in cancer therapy

31 March 2020

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Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

31 March 2020

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A microarray-based genetic screen for yeast chronological aging factors

31 March 2020

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Autophagy regulates ageing in C. elegans.

31 March 2020

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Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and -independent pathways

31 March 2020

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Autophagy in aging, disease and death: the true identity of a cell death impostor

31 March 2020

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With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging

31 March 2020

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The dynamic nature of autophagy in cancer

31 March 2020

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The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming

31 March 2020

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Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence.

31 March 2020

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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

31 March 2020

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Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

31 March 2020

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Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells

31 March 2020

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Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy

31 March 2020

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31 March 2020

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A cytoplasmic PML mutant inhibits p53 function

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Regulation of autophagy by cytoplasmic p53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Negative regulation of autophagy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

The effects of p53 on whole organism longevity are mediated by autophagy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

The critical role of catalase in prooxidant and antioxidant function of p53.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

A model for p53-induced apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Transcriptional activation of the human glutathione peroxidase promoter by p53.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Homeostatic functions of the p53 tumor suppressor: regulation of energy metabolism and antioxidant defense

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Reactive oxygen species are downstream mediators of p53-dependent apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Influence of induced reactive oxygen species in p53-mediated cell fate decisions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Neurodegenerative processes in Huntington's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Mitochondrial dysfunction as a cause of ageing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Telomere dysfunction induces metabolic and mitochondrial compromise.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Mitochondria and the autophagy-inflammation-cell death axis in organismal aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

The pathways of mitophagy for quality control and clearance of mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

SIRT1, is it a tumor promoter or tumor suppressor?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Negative control of p53 by Sir2alpha promotes cell survival under stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p53-family proteins and their regulators: hubs and spokes in tumor suppression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

SIRT1 stabilizes PML promoting its sumoylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Sirtuin catalysis and regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Sirtuins as regulators of metabolism and healthspan

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Sirt1 modulates premature senescence-like phenotype in human endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

How does SIRT1 affect metabolism, senescence and cancer?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Pseudo-DNA damage response in senescent cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

SirT1 gain of function increases energy efficiency and prevents diabetes in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Therapeutic targets in cancer cell metabolism and death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Hallmarks of Cancer: The Next Generation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Senescence in tumours: evidence from mice and humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

STAT3 can serve as a hit in the process of malignant transformation of primary cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Temporal dissection of tumorigenesis in primary cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Strategies for therapeutic targeting of the p53 pathway in cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Restoration of p53 function leads to tumour regression in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Blockade of Hsp90 by 17AAG antagonizes MDMX and synergizes with Nutlin to induce p53-mediated apoptosis in solid tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Chk2 mediates RITA-induced apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Selective activation of p53-mediated tumour suppression in high-grade tumours

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Stage-specific sensitivity to p53 restoration during lung cancer progression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Chronic treatment with resveratrol induces redox stress- and ataxia telangiectasia-mutated (ATM)-dependent senescence in p53-positive cancer cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Resveratrol and life extension.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Short telomeres limit tumor progression in vivo by inducing senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

PRAK is essential for ras-induced senescence and tumor suppression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

A survey of telomerase activity in human cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p63 and p73, the ancestors of p53.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p73: Friend or foe in tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

c-Abl tyrosine kinase in the DNA damage response: cell death and more

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Regulation of p73 activity by post-translational modifications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p73 induces apoptosis by different mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p73 is critical for the persistence of memory

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p73: a multifunctional protein in neurobiology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

TAp73 acts via the bHLH Hey2 to promote long-term maintenance of neural precursors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

microRNA-34a regulates neurite outgrowth, spinal morphology, and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p73 suppresses polyploidy and aneuploidy in the absence of functional p53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

TAp63 and DeltaNp63 in cancer and epidermal development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

miR-203 represses 'stemness' by repressing DeltaNp63

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p63 Is essential for the proliferative potential of stem cells in stratified epithelia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

A skin microRNA promotes differentiation by repressing 'stemness'.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p63 in epithelial development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

ΔNp63 is an ectodermal gatekeeper of epidermal morphogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

ΔNp63α regulates keratinocyte proliferation by controlling PTEN expression and localization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p63 protects the female germ line during meiotic arrest

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p63 is a p53 homologue required for limb and epidermal morphogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p63 deficiency activates a program of cellular senescence and leads to accelerated aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Role of the promyelocytic leukaemia protein in cell death regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

TAp63 prevents premature aging by promoting adult stem cell maintenance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Regulation of skin aging and heart development by TAp63.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

TAp63 induces senescence and suppresses tumorigenesis in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

p63-microRNA feedback in keratinocyte senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Axis of ageing: telomeres, p53 and mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

The role of reactive oxygen species and autophagy in safingol-induced cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Induction of reactive oxygen species-mediated autophagy by a novel microtubule-modulating agent

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Bmi1 regulates mitochondrial function and the DNA damage response pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

Extension of murine life span by overexpression of catalase targeted to mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

TAp63 is a master transcriptional regulator of lipid and glucose metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.640

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.640

1 reference

Dimensions Publication ID

28 August 2017

1012361722

0 references

1 reference