(Q46785611)

English

In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc

scientific article published in November 2005

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc (English)

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

Alzheimer's disease

0 references

Anthony R. White

6

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

Colin L. Masters

7

object named as

Colin L Masters

1 reference

Europe PubMed Central

25 December 2017

author name string

David E Hoke

1

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

Jiang-Li Tan

2

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

Nancy T Ilaya

3

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

Janetta G Culvenor

4

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

Stephanie J Smith

5

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

Geneviève M Evin

8

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

language of work or name

0 references

publication date

1 November 2005

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

272

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

5544-5557

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

21

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Biogenesis and metabolism of Alzheimer's disease Abeta amyloid peptides

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

The role of presenilin cofactors in the gamma-secretase complex

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Purification and characterization of the human gamma-secretase complex

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Generation of beta A4 from the amyloid protein precursor and fragments thereof

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

The metallobiology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Cholesterol and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Estrogen decreases zinc transporter 3 expression and synaptic vesicle zinc levels in mouse brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Neuronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

In vivo reduction of amyloid-beta by a mutant copper transporter

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2005.04950.X

21 January 2018

Identifiers

10.1111/J.1742-4658.2005.04950.X

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16262694

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q46785611&oldid=2131203292"