(Q46863464)

English

Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas

scientific article published on 9 October 2012

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas (English)

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

mitochondrial DNA

0 references

Claudio Ceccarelli

6

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

9

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Giovanni Tallini

12

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

object named as

Ivana Kurelac

1

0 references

Jorge Reis-Filho

13

object named as

Jorge S Reis-Filho

1 reference

Europe PubMed Central

25 December 2017

author name string

Alan MacKay

2

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Maryou B K Lambros

3

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Erica Di Cesare

4

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Giovanna Cenacchi

5

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Isabella Morra

7

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Antonio Melcarne

8

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Francesco Maria Calabrese

10

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Marcella Attimonelli

11

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Giuseppe Gasparre

14

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

publication date

9 October 2012

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Human Molecular Genetics

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

22

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

2

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

226-238

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

Evaluating mitochondrial DNA in cancer occurrence and development

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Learning from oncocytic tumors: Why choose inefficient mitochondria?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

[Cytogenetic alterations in renal tumors. Applications for comparative genomic hybridization and fluorescence in situ hybridization].

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Pathohistological classification of pituitary tumors: 10 years of experience with the German Pituitary Tumor Registry

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Prevalence and incidence of pituitary adenomas

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Overview of genetic testing in patients with pituitary adenomas.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Mitochondrial DNA mutation in normal margins and tumors of recurrent head and neck squamous cell carcinoma patients

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Somatic mutations of the mitochondrial genome in human breast cancers

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Heteroplasmic mitochondrial DNA mutations in normal and tumour cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Two distinct thyroid tumours in a patient with Cowden syndrome carrying both a 10q23 and a mitochondrial DNA germline deletion.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Respiratory chain complex I is a mitochondrial tumor suppressor of oncocytic tumors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

A mitochondrial DNA tRNA(Val) point mutation associated with adult-onset Leigh syndrome.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Searching for a needle in the haystack: comparing six methods to evaluate heteroplasmy in difficult sequence context

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Allele specific locked nucleic acid quantitative PCR (ASLNAqPCR): an accurate and cost-effective assay to diagnose and quantify KRAS and BRAF mutation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

HmtDB, a genomic resource for mitochondrion-based human variability studies

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

The epidemiology and genetics of pituitary adenomas

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Pituitary tumours: findings from whole genome analyses

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

p53: guardian of ploidy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Non-functioning pituitary adenomas infrequently harbor G-protein gene mutations.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Cytogenetic alterations in pituitary adenomas detected by comparative genomic hybridization

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Multiple genetic aberrations including evidence of chromosome 11q13 rearrangement detected in pituitary adenomas by comparative genomic hybridization

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Increased chromosomal imbalances in recurrent pituitary adenomas.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Involvement of the chromosomal region 11q13 in renal oncocytoma: case report and literature review

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Anterior pituitary adenomas: inherited syndromes, novel genes and molecular pathways

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

G-protein and signalling in pituitary tumours

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Mutation of C20orf7 disrupts complex I assembly and causes lethal neonatal mitochondrial disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Mutations in the gene encoding C8orf38 block complex I assembly by inhibiting production of the mitochondria-encoded subunit ND1

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Overexpression of HMGA2 relates to reduction of the let-7 and its relationship to clinicopathological features in pituitary adenomas

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Pituitary tumor-transforming gene and its binding factor in endocrine cancer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Cell cycle control of pituitary development and disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Chromosomal aberrations by comparative genomic hybridization in hürthle cell thyroid carcinomas are associated with tumor recurrence

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Oncocytes, oxyphils, Hürthle, and Askanazy cells: morphological and molecular features of oncocytic thyroid nodules

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Molecular features of thyroid oncocytic tumors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Oncocytic change in pleomorphic adenoma: molecular evidence in support of an origin in neoplastic cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Systematic identification of human mitochondrial disease genes through integrative genomics

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Dok-7 mutations underlie a neuromuscular junction synaptopathy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Dok-7 myasthenia: phenotypic and molecular genetic studies in 16 patients

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Germline mutation in DOK7 associated with fetal akinesia deformation sequence

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra-tumour genetic heterogeneity and clonal selection

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

A multiplex PCR predictor for aCGH success of FFPE samples

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

A "Copernican" reassessment of the human mitochondrial DNA tree from its root

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

mtDNA tree Build 17 (18 Feb 2016)

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Real-time detection and quantification of mitochondrial mutations with oligonucleotide primers containing locked nucleic acid

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Resolving the resolution of array CGH.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Immunophenotypic and genomic characterization of papillary carcinomas of the breast

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

A novel heteroplasmic tRNA(Leu(CUN)) mtDNA point mutation associated with chronic progressive external ophthalmoplegia.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Oncocytic carcinoma of the breast: frequency, morphology and follow-up

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS422

21 January 2018

Identifiers

10.1093/HMG/DDS422

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/23049073

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q46863464&oldid=2135214849"