(Q47765737)

5 February 2018

title

T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. (English)

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5 February 2018

4

Emil R Unanue

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5 February 2018

author name string

Zheng Pu

series ordinal

1

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5 February 2018

Scott B Lovitch

series ordinal

2

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5 February 2018

Elizabeth K Bikoff

series ordinal

3

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5 February 2018

language of work or name

English

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publication date

1 April 2004

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5 February 2018

published in

Immunity

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5 February 2018

volume

20

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5 February 2018

issue

4

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5 February 2018

page(s)

467-476

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5 February 2018

Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope

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Cutting edge: TCR contacts as anchors: effects on affinity and HLA-DM stability

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The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues

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Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT)

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7 January 2021

Exogenously provided peptides of a self-antigen can be processed into forms that are recognized by self-T cells

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7 January 2021

Formation of two peptide/MHC II isomers is catalyzed differentially by HLA-DM.

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7 January 2021

Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain.

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7 January 2021

Accessory molecules for MHC class II peptide loading

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7 January 2021

Stabilization of soluble, low-affinity HLA-DM/HLA-DR1 complexes by leucine zippers

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7 January 2021

T cell receptor recognition of MHC class II-bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage

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7 January 2021

Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments

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7 January 2021

Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides

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7 January 2021

HLA-DM recognizes the flexible conformation of major histocompatibility complex class II.

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7 January 2021

Deamidation of asparagine in a major histocompatibility complex-bound peptide affects T cell recognition but does not explain type B reactivity

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7 January 2021

pH-sensitive liposomes: acid-induced liposome fusion

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7 January 2021

A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes

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https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Assembly, transport, and function of MHC class II molecules

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7 January 2021

Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes

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7 January 2021

HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

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7 January 2021

X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II

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7 January 2021

HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

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7 January 2021

Novel mutants define genes required for the expression of human histocompatibility leukocyte antigen DM: evidence for loci on human chromosome 6p

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7 January 2021

Crystal structure of I-Ak in complex with a dominant epitope of lysozyme

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7 January 2021

Crystal structure of mouse H2-M

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7 January 2021

Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells

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https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au

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7 January 2021

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

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7 January 2021

Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1

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7 January 2021

T cell recognition of distinct peptide:I-Au conformers in murine experimental autoimmune encephalomyelitis.

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7 January 2021

The cell biology of antigen presentation

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7 January 2021

DM loss in k haplotype mice reveals isotype-specific chaperone requirements

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7 January 2021

HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice

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https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Hindering auxiliary anchors are potent modulators of peptide binding and selection by I-Ak class II molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Distinct antigen MHC class II complexes generated by separate processing pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

APCs present A beta(k)-derived peptides that are autoantigenic to type B T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Cutting edge: H-2DM is responsible for the large differences in presentation among peptides selected by I-Ak during antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Radioiodination of proteins by the use of the chloramine-T method

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7 January 2021

Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Quantitative analysis of the T cell repertoire that escapes negative selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Clonal analysis of B- and T-cell responses to Ia antigens. I. Topology of epitope regions on I-Ak and I-Ek molecules analyzed with 35 monoclonal alloantibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Peptide loading onto recycling HLA-DR molecules occurs in early endosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Neutrophils process exogenous bacteria via an alternate class I MHC processing pathway for presentation of peptides to T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Distinct recognition by two subsets of T cells of an MHC class II-peptide complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

The crystal structure of a T cell receptor in complex with peptide and MHC class II

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Inhibition of invariant chain (Ii)-calnexin interaction results in enhanced degradation of Ii but does not prevent the assembly of alpha beta Ii complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Intracellular assembly and transport of endogenous peptide-MHC class II complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Extracellular antigen processing and presentation by immature dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Dominance and crypticity of T cell antigenic determinants

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Mediation by HLA-DM of dissociation of peptides from HLA-DR

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Interaction between HLA-DM and HLA-DR involves regions that undergo conformational changes at lysosomal pH.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Perspective on antigen processing and presentation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Conformational alterations during biosynthesis of HLA-DR3 molecules controlled by invariant chain and HLA-DM.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Identification of a major I-Ek-restricted determinant of hen egg lysozyme: limitations of lymph node proliferation studies in defining immunodominance and crypticity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Altered positive selection due to corecognition of floppy peptide/MHC II conformers supports an integrative model of thymic selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

The kinetic basis of peptide exchange catalysis by HLA-DM

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900073-1

7 January 2021

10.1016/S1074-7613(04)00073-1

Identifiers

DOI

1 reference

5 February 2018

1 reference

5 February 2018