(Q47994244)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003604%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Engineered protein function by selective amino acid diversification (English)

1 reference

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25 December 2019

5

1 reference

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25 December 2019

author name string

Jeremy Minshull

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003604%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Sridhar Govindarajan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003604%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Tony Cox

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003604%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Jon E Ness

4

1 reference

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25 December 2019

publication date

1 April 2004

1 reference

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25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003604%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003604%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

4

1 reference

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25 December 2019

page(s)

416-427

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003604%20AND%20SRC:MED&resulttype=core&format=json

The art and design of genetic screens: caenorhabditis elegans

25 December 2019

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Cellular signalling and the complexity of biological timing: insights from the ultradian clock of Schizosaccharomyces pombe

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Usage of activating mutations in the analysis of cytokine signal transduction pathways

7 January 2021

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Purification, characterization and identification of cysteine desulfhydrase of Corynebacterium glutamicum, and its relationship to cysteine production

7 January 2021

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Metabolic engineering for microbial production of aromatic amino acids and derived compounds

7 January 2021

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The mutation of two amino acid residues in the N-terminus of tyrosine hydroxylase (TH) dramatically enhances the catalytic activity in neuroendocrine AtT-20 cells

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Differential regulation of metabotropic glutamate receptor 5-mediated phosphoinositide hydrolysis and extracellular signal-regulated kinase responses by protein kinase C in cultured astrocytes

7 January 2021

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7 January 2021

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Cutting edge: a chemical genetic system for the analysis of kinases regulating T cell development

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Microbial systems and directed evolution of protein activities

7 January 2021

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THE RELATION OF RECOMBINATION TO MUTATIONAL ADVANCE

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7 January 2021

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Catalytic properties of class A beta-lactamases: efficiency and diversity

7 January 2021

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Rapid evolution of a protein in vitro by DNA shuffling

7 January 2021

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Beyond binding: using phage display to select for structure, folding and enzymatic activity in proteins

7 January 2021

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Cell-Surface display of heterologous proteins: From high-throughput screening to environmental applications

7 January 2021

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Protein engineering by cell-surface display

7 January 2021

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7 January 2021

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High-throughput screening of enzyme libraries

7 January 2021

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Quantitative screening of yeast surface-displayed polypeptide libraries by magnetic bead capture

7 January 2021

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A fluorescence polarization assay for native protein substrates of kinases

7 January 2021

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High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction

7 January 2021

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An enzyme-linked immunosorbent assay for the Raf/MEK1/MAPK signaling cascade

7 January 2021

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Phosphorylation-directed antibodies in high-flux screens for compounds that modulate signal transduction

7 January 2021

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Screening for gene regulation mutants by bioluminescence imaging.

7 January 2021

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Expression of cre recombinase as a reporter of signal transduction in mammalian cells

7 January 2021

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DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution

7 January 2021

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Improved green fluorescent protein by molecular evolution using DNA shuffling

7 January 2021

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7 January 2021

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Evolution of a human immunodeficiency virus type 1 variant with enhanced replication in pig-tailed macaque cells by DNA shuffling

7 January 2021

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A general and rapid mutagenesis method using polymerase chain reaction

7 January 2021

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Optimizing the search algorithm for protein engineering by directed evolution

7 January 2021

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Random DNA fragmentation with endonuclease V: application to DNA shuffling

7 January 2021

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Different structural requirements for plasminogen activator inhibitor 1 (PAI-1) during latency transition and proteinase inhibition as evidenced by phage-displayed hypermutated PAI-1 libraries

7 January 2021

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Sequences in the Intracellular Loops of the Yeast Pheromone Receptor Ste2p Required for G Protein Activation†

7 January 2021

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Acetylcholinesterase engineering for detection of insecticide residues

7 January 2021

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Why are proteins so robust to site mutations?

7 January 2021

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7 January 2021

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Synthetic shuffling expands functional protein diversity by allowing amino acids to recombine independently

7 January 2021

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Heteroduplexes in mixed-template amplifications: formation, consequence and elimination by 'reconditioning PCR'

7 January 2021

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7 January 2021

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DNA shuffling of subgenomic sequences of subtilisin

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Systematic variation of amino acid substitutions for stringent assessment of pairwise covariation

7 January 2021

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Assembly of designed oligonucleotides as an efficient method for gene recombination: a new tool in directed evolution

7 January 2021

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Growth factor engineering by degenerate homoduplex gene family recombination

7 January 2021

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Engineering of a macromolecular scaffold to develop specific protease inhibitors

7 January 2021

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Putting engineering back into protein engineering: bioinformatic approaches to catalyst design.

7 January 2021

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Optimising the signal peptide for glycosyl phosphatidylinositol modification of human acetylcholinesterase using mutational analysis and peptide-quantitative structure-activity relationships

7 January 2021

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Amino acid substitution during functionally constrained divergent evolution of protein sequences.

7 January 2021

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A quantitative structure-activity relationship study of some substance P-related peptides A multivariate approach using PLS and variable selection

7 January 2021

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7 January 2021

https://api.crossref.org/works/10.1016%2FJ.YMETH.2003.10.004

inferred from DOI database lookup

7 January 2021

based on heuristic

Surveying a local fitness landscape of a protein with epistatic sites for the study of directed evolution

1 reference

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Quantitative sequence-activity models (QSAM)--tools for sequence design

7 January 2021

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A hierarchical approach to protein molecular evolution

7 January 2021

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Real experiences of uHTS: a prototypic 1536-well fluorescence anisotropy-based uHTS screen and application of well-level quality control procedures

7 January 2021

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Automated assay optimization with integrated statistics and smart robotics.

7 January 2021

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Rescue of a severely bottlenecked wolf (Canis lupus) population by a single immigrant.

7 January 2021

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The genetic contribution of single male immigrants to small, inbred populations: a laboratory study using Drosophila melanogaster

7 January 2021

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Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling

7 January 2021

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Randomization of genes by PCR mutagenesis

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YMETH.2003.10.004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15003604%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference