(Q48257215)

10 February 2018

title

Responsible innovation in human germline gene editing: Background document to the recommendations of ESHG and ESHRE. (English)

1 reference

10 February 2018

14

Martina C Cornel

1 reference

10 February 2018

Ursula Eichenlaub-Ritter

5

Ursula Eichenlaub-Ritter

1 reference

10 February 2018

8

Mariëtte Goddijn

1 reference

10 February 2018

9

Heidi C Howard

1 reference

10 February 2018

Emmanuelle Rial-Sebbag

11

Emmanuelle Rial-Sebbag

1 reference

10 February 2018

Guido Pennings

3

Guido Pennings

1 reference

10 February 2018

Wybo Dondorp

12

Wybo Dondorp

1 reference

10 February 2018

Francesca Forzano

7

Francesca Forzano

1 reference

10 February 2018

Björn Heindryckx

2

Björn Heindryckx

1 reference

10 February 2018

author name string

Guido De Wert

1

1 reference

10 February 2018

Angus Clarke

4

1 reference

10 February 2018

Carla G van El

6

1 reference

10 February 2018

Dragica Radojkovic

10

1 reference

10 February 2018

Basil C Tarlatzis

13

1 reference

10 February 2018

European Society of Human Genetics and the European Society of Human Reproduction and Embryology

15

1 reference

10 February 2018

publication date

12 January 2018

1 reference

10 February 2018

European Journal of Human Genetics

published in

1 reference

10 February 2018

https://scigraph.springernature.com/pub.10.1038/s41431-017-0077-z

exact match

0 references

cites work

CRISPR: gene editing is just the beginning.

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

CRISPR gene-editing tested in a person for the first time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Global summit reveals divergent views on human gene editing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

US science advisers outline path to genetically modified babies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Genome engineering through CRISPR/Cas9 technology in the human germline and pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

CRISPR/Cas9 nuclease-mediated gene knock-in in bovine-induced pluripotent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Correction of a genetic disease in mouse via use of CRISPR-Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Generation of a monkey with MECP2 mutations by TALEN-based gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

International regulatory landscape and integration of corrective genome editing into in vitro fertilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Correction of a pathogenic gene mutation in human embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

BATCH-GE: Batch analysis of Next-Generation Sequencing data for genome editing assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Spermatogonial stem cell preservation and transplantation: from research to clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Isolation, characterization and propagation of mitotically active germ cells from adult mouse and human ovaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

The post-inner cell mass intermediate: implications for stem cell biology and assisted reproductive technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Reconstitution in vitro of the entire cycle of the mouse female germ line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Modulating mitochondrial quality in disease transmission: towards enabling mitochondrial DNA disease carriers to have healthy children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Genetic Drift Can Compromise Mitochondrial Replacement by Nuclear Transfer in Human Oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Live birth derived from oocyte spindle transfer to prevent mitochondrial disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Selective elimination of mitochondrial mutations in the germline by genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

SOX17 is a critical specifier of human primordial germ cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Oocyte activation, phospholipase C zeta and human infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Common variants spanning PLK4 are associated with mitotic-origin aneuploidy in human embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Mitochondrial replacement therapy: the UK and US regulatory landscapes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Mitochondrial replacement therapy in reproductive medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Human embryonic stem cells: research, ethics and policy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

I. The moral status of the pre-implantation embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

What if stem cells turn into embryos in a dish?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Embryology policy: Revisit the 14-day rule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

ESHRE Task Force on Ethics and Law 12: oocyte donation for non-reproductive purposes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Towards a European consensus for reporting incidental findings during clinical NGS testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

ESHRE Task Force on Ethics and Law 13: the welfare of the child in medically assisted reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

The moral imperative to continue gene editing research on human embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Ethics and germline gene editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Comprehensive pre-implantation genetic screening: ethical reflection urgently needed.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Designing babies through gene editing: science or science fiction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Meta-analysis of the heritability of human traits based on fifty years of twin studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Human gene therapy: why draw a line?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Germ-line gene modification and disease prevention: some medical and ethical perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Modification of the Embryo's Genome: More Useful in Research Than in the Clinic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

Human germline gene editing: Recommendations of ESHG and ESHRE.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5891502

Highly Efficient Mouse Genome Editing by CRISPR Ribonucleoprotein Electroporation of Zygotes

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5891502

Efficient Mitochondrial Genome Editing by CRISPR/Cas9.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5891502

Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5891502

Antagonistic pleiotropy as a widespread mechanism for the maintenance of polymorphic disease alleles

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5891502

Intrafamilial medically assisted reproduction

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5891502

Protecting the endangered human: toward an international treaty prohibiting cloning and inheritable alterations.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5891502

IVF: regulation or prohibition?

2 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

GENETIC TECHNOLOGY REGULATION. Editing policy to fit the genome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

7 January 2021

inferred from DOI database lookup

Innovative reproductive technologies: risks and responsibilities

1 reference

https://api.crossref.org/works/10.1038%2FS41431-017-0077-Z

7 January 2021

inferred from DOI database lookup

Heredity: science and society on the possibilities and limits of genetic testing and gene therapy. Report issued by a Committee of the Health Council of The Netherlands

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29326429

12 December 2020

inferred from PubMed ID database lookup

Convention for the protection of human rights and dignity of the human being with regard to the application of biology and medicine: convention on human rights and biomedicine (adopted by the Committee of Ministers on 19 November 1996). Council of E

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29326429

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41431-017-0077-Z

1 reference

10 February 2018

release_ksryel2ydfciran3irgl7mkc6e

Fatcat ID

0 references

PMC publication ID

5891502

0 references

1 reference

10 February 2018