(Q48500475)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29423743%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

title

Synthetic biology of polyketide synthases (English)

1 reference

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15 March 2020

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Satoshi Yuzawa

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29423743%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

Leonard Katz

series ordinal

4

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15 March 2020

publication date

9 February 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29423743%20AND%20SRC:MED&resulttype=core&format=json

Journal of Industrial Microbiology & Biotechnology

15 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29423743%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

volume

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29423743%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

issue

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29423743%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

page(s)

621-633

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29423743%20AND%20SRC:MED&resulttype=core&format=json

Novel avermectins produced by mutational biosynthesis.

15 March 2020

cites work

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12 December 2020

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

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12 December 2020

Stereospecific acyl transfers on the erythromycin-producing polyketide synthase

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12 December 2020

Evidence for a double-helical structure for modular polyketide synthases.

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12 December 2020

The Molecular Basis of Celmer's Rules: The Stereochemistry of the Condensation Step in Chain Extension on the Erythromycin Polyketide Synthase†

1 reference

12 December 2020

The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.

1 reference

12 December 2020

Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.

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12 December 2020

Dissecting and exploiting intermodular communication in polyketide synthases

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12 December 2020

Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis

1 reference

12 December 2020

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

1 reference

12 December 2020

Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15.

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12 December 2020

Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules

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12 December 2020

Biosynthesis and attachment of novel bacterial polyketide synthase starter units

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12 December 2020

A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin

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12 December 2020

Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization

1 reference

12 December 2020

Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula

1 reference

12 December 2020

Engineered biosynthesis of geldanamycin analogs for Hsp90 inhibition.

1 reference

12 December 2020

Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes.

1 reference

12 December 2020

Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase

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12 December 2020

Rational design and assembly of synthetic trimodular polyketide synthases.

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12 December 2020

Structure and mechanism of the 6-deoxyerythronolide B synthase

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12 December 2020

PKS and NRPS release mechanisms

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12 December 2020

Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters

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12 December 2020

Mutagenesis of a modular polyketide synthase enoylreductase domain reveals insights into catalysis and stereospecificity

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12 December 2020

Stereospecificity of the dehydratase domain of the erythromycin polyketide synthase

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12 December 2020

Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity

1 reference

12 December 2020

The Missing Linker: A Dimerization Motif Located within Polyketide Synthase Modules

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12 December 2020

Broad substrate specificity of the loading didomain of the lipomycin polyketide synthase

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12 December 2020

Enzyme analysis of the polyketide synthase leads to the discovery of a novel analog of the antibiotic α-lipomycin.

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12 December 2020

In vitro analysis of carboxyacyl substrate tolerance in the loading and first extension modules of borrelidin polyketide synthase.

1 reference

12 December 2020

Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering

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12 December 2020

Divergent mechanistic routes for the formation of gem-dimethyl groups in the biosynthesis of complex polyketides.

1 reference

12 December 2020

An acyltransferase domain of FK506 polyketide synthase recognizing both an acyl carrier protein and coenzyme A as acyl donors to transfer allylmalonyl and ethylmalonyl units

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12 December 2020

Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces

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12 December 2020

Engineering a Polyketide Synthase for In Vitro Production of Adipic Acid.

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12 December 2020

Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology

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12 December 2020

Stereocontrol within polyketide assembly lines

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12 December 2020

Biosynthesis of polyketides by trans-AT polyketide synthases

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12 December 2020

Alteration of Polyketide Stereochemistry from anti to syn by a Ketoreductase Domain Exchange in a Type I Modular Polyketide Synthase Subunit.

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12 December 2020

Protein-Protein Interactions, Not Substrate Recognition, Dominate the Turnover of Chimeric Assembly Line Polyketide Synthases

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12 December 2020

Structure and mechanism of assembly line polyketide synthases

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12 December 2020

Broadening substrate specificity of a chain-extending ketosynthase through a single active-site mutation.

1 reference

12 December 2020

Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production.

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12 December 2020

Development of Next Generation Synthetic Biology Tools for Use in Streptomyces venezuelae.

1 reference

12 December 2020

A New Era of Genome Integration-Simply Cut and Paste!

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12 December 2020

Towards Precision Engineering of Canonical Polyketide Synthase Domains: Recent Advances and Future Prospects

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12 December 2020

The Uncommon Enzymology of Cis-Acyltransferase Assembly Lines

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12 December 2020

Elucidation of the Stereospecificity of C-Methyltransferases from trans-AT Polyketide Synthases

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12 December 2020

Elucidation of the Cryptic Methyl Group Epimerase Activity of Dehydratase Domains from Modular Polyketide Synthases Using a Tandem Modules Epimerase Assay

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12 December 2020

ClusterCAD: a computational platform for type I modular polyketide synthase design.

1 reference

12 December 2020

Diversity oriented biosynthesis via accelerated evolution of modular gene clusters.

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12 December 2020

Engineered polyketides: Synergy between protein and host level engineering.

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12 December 2020

10.1007/S10295-018-2021-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29423743%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

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