(Q48509192)

12 February 2018

http://europepmc.org/abstract/MED/27307197

title

Broadening substrate specificity of a chain-extending ketosynthase through a single active-site mutation (English)

1 reference

12 February 2018

http://europepmc.org/abstract/MED/27307197

author

Bill Broadhurst

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Annabel C Murphy

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Hui Hong

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Steve Vance

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Peter F Leadlay

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

language of work or name

English

0 references

publication date

16 June 2016

1 reference

12 February 2018

http://europepmc.org/abstract/MED/27307197

published in

Chemical Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

8373-8376

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

Reinvigorating natural product combinatorial biosynthesis with synthetic biology

8 June 2020

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The biosynthetic logic of polyketide diversity

21 January 2018

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4-[2-(2-amino-2-oxoethyl)-2,7-dihydroxy-4-oxochroman-5-yl]-3-hydroxybut-2-enoic acid

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Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules

21 January 2018

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Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases.

21 January 2018

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Multifactorial control of iteration events in a modular polyketide assembly line

21 January 2018

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Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

21 January 2018

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A Close Look at a Ketosynthase from a Trans-Acyltransferase Modular Polyketide Synthase

21 January 2018

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Acyl-chain elongation drives ketosynthase substrate selectivity in trans-acyltransferase polyketide synthases.

21 January 2018

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The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.

21 January 2018

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Structural and Mechanistic Analysis of Protein Interactions in Module 3 of the 6-Deoxyerythronolide B Synthase

21 January 2018

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Vinylogous chain branching catalysed by a dedicated polyketide synthase module

21 January 2018

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Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans

21 January 2018

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A novel mycolactone from a clinical isolate of Mycobacterium ulcerans provides evidence for additional toxin heterogeneity as a result of specific changes in the modular polyketide synthase

21 January 2018

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Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria

21 January 2018

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The cell wall-associated mycolactone polyketide synthases are necessary but not sufficient for mycolactone biosynthesis

21 January 2018

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Transfer, stable maintenance and expression of the mycolactone polyketide megasynthase mls genes in a recombination-impaired Mycobacterium marinum

21 January 2018

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Structure of a modular polyketide synthase

21 January 2018

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21 January 2018

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Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase

21 January 2018

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Promiscuity of a modular polyketide synthase towards natural and non-natural extender units.

21 January 2018

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Quantitative full time course analysis of nonlinear enzyme cycling kinetics

21 January 2018

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Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1039/C6CC03501A

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27307197%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference