(Q37888493)

24 August 2017

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title

Metabolic engineering is key to a sustainable chemical industry (English)

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24 August 2017

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Annabel C Murphy

1

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24 August 2017

publication date

13 June 2011

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24 August 2017

published in

Natural Product Reports

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24 August 2017

volume

28

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24 August 2017

issue

8

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24 August 2017

page(s)

1406-1425

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Polyhydroxyalkanoates: bioplastics with a green agenda

24 August 2017

cites work

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The atom economy--a search for synthetic efficiency

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The advent and development of organocatalysis

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Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry

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Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation

21 January 2018

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Sitagliptin manufacture: a compelling tale of green chemistry, process intensification, and industrial asymmetric catalysis.

21 January 2018

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Evidence for S. cerevisiae fermentation in ancient wine

21 January 2018

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Fermentative production of butanol--the industrial perspective

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Biocatalysis--key to sustainable industrial chemistry

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Mining genomes and 'metagenomes' for novel catalysts

21 January 2018

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Metagenomic era for biocatalyst identification

21 January 2018

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Directed evolution of enantioselective enzymes: an unconventional approach to asymmetric catalysis in organic chemistry

21 January 2018

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Recent progress in industrial biocatalysis

21 January 2018

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Status of protein engineering for biocatalysts: how to design an industrially useful biocatalyst

21 January 2018

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Industrial biocatalysis today and tomorrow

21 January 2018

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Cross-linked enzyme aggregates (CLEAs): stable and recyclable biocatalysts

21 January 2018

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Biocatalysis in the gas phase

21 January 2018

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Chemoenzymatic synthesis of building blocks for statin side chains

21 January 2018

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Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates

21 January 2018

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Nitrile hydratase and its application to industrial production of acrylamide

21 January 2018

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Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture

21 January 2018

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The optimization of penicillin biosynthesis in fungi

21 January 2018

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https://api.crossref.org/works/10.1039%2FC1NP00029B

Industrial production of beta-lactam antibiotics

21 January 2018

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https://api.crossref.org/works/10.1039%2FC1NP00029B

Environmentally safe production of 7-ACA by recombinant Acremonium chrysogenum

21 January 2018

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Biotechnological production and applications of statins

21 January 2018

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Biocatalysis in development of green pharmaceutical processes

21 January 2018

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Efficient synthesis of simvastatin by use of whole-cell biocatalysis

21 January 2018

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Rational improvement of simvastatin synthase solubility in Escherichia coli leads to higher whole-cell biocatalytic activity.

21 January 2018

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Improvement of erythromycin production by Saccharopolyspora erythraea in molasses based medium through cultivation medium optimization

21 January 2018

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https://api.crossref.org/works/10.1039%2FC1NP00029B

Three biotechnical processes using Ashbya gossypii, Candida famata, or Bacillus subtilis compete with chemical riboflavin production

21 January 2018

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https://api.crossref.org/works/10.1039%2FC1NP00029B

The use of microorganisms in L-ascorbic acid production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Biotechnological production of itaconic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Microbial production of building block chemicals and polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Synthesis of ecteinascidin ET-743 and phthalascidin Pt-650 from cyanosafracin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Development of Yondelis (trabectedin, ET-743). A semisynthetic process solves the supply problem.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

21 January 2018

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https://api.crossref.org/works/10.1039%2FC1NP00029B

Mutational biosynthesis--a tool for the generation of structural diversity in the biosynthesis of antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Mutasynthesis - uniting chemistry and genetics for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

An expeditious route to fluorinated rapamycin analogues by utilising mutasynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Semisynthetic production of unnatural L-alpha-amino acids by metabolic engineering of the cysteine-biosynthetic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Combinatorial biosynthesis of reduced polyketides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Mining and engineering natural-product biosynthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Combinatorial biosynthesis--potential and problems

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Combinatorial biosynthesis for drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Revisiting the modularity of modular polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Generation of new epothilones by genetic engineering of a polyketide synthase in Myxococcus xanthus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Combinatorial biosynthesis of novel antibiotics related to daptomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Genetic engineering in Streptomyces roseosporus to produce hybrid lipopeptide antibiotics

21 January 2018

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https://api.crossref.org/works/10.1039%2FC1NP00029B

Production of hybrid 16-membered macrolides by expressing combinations of polyketide synthase genes in engineered Streptomyces fradiae hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC1NP00029B

Structure-based dissociation of a type I polyketide synthase module

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

The structural basis for docking in modular polyketide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis

21 January 2018

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Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties

21 January 2018

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Production of the antitumor drug epirubicin (4'-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius

21 January 2018

1 reference

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Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Biocatalytic conversion of avermectin to 4''-oxo-avermectin: improvement of cytochrome p450 monooxygenase specificity by directed evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Tamiflu: the supply problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Benzene-free synthesis of adipic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Major proteins related to chlortetracycline biosynthesis in a Streptomyces aureofaciens production strain studied by quantitative proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Engineering Escherichia coli for efficient conversion of glucose to pyruvate

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Indigo - 100 Jahre industrielle Synthese

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Application of metabolic engineering to improve both the production and use of biotech indigo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Metabolic engineering for the microbial production of 1,3-propanediol

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Trends for diverse production strategies of plant medicinal alkaloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Metabolic engineering of natural products in plants; tools of the trade and challenges for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Volatile science? Metabolic engineering of terpenoids in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Suppression of a P450 hydroxylase gene in plant trichome glands enhances natural-product-based aphid resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Disease resistance results from foreign phytoalexin expression in a novel plant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Engineering oilseeds for sustainable production of industrial and nutritional feedstocks: solving bottlenecks in fatty acid flux.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Metabolic engineering of isoprenoid biosynthesis in Arabidopsis for the production of taxadiene, the first committed precursor of Taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Development and application of medicinal plant tissue cultures for production of drugs and herbal medicinals in China.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Cultured cambial meristematic cells as a source of plant natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Metabolic reprogramming of periwinkle plant culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Integrating carbon-halogen bond formation into medicinal plant metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Metabolic engineering for plant natural product biosynthesis in microbes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Production of plant-specific flavanones by Escherichia coli containing an artificial gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Exploring recombinant flavonoid biosynthesis in metabolically engineered Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Synthesis of unnatural flavonoids and stilbenes by exploiting the plant biosynthetic pathway in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Production of curcuminoids by Escherichia coli carrying an artificial biosynthesis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Combinatorial biosynthesis of plant medicinal polyketides by microorganisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

A simple conversion of artemisinic acid into artemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Where chemistry meets biology: the chemoenzymatic synthesis of nonribosomal peptides and polyketides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Programming peptidomimetic syntheses by translating genetic codes designed de novo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Messenger RNA-programmed incorporation of multiple N-methyl-amino acids into linear and cyclic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Methods and options for the heterologous production of complex natural products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Genetically modified bacterial strains and novel bacterial artificial chromosome shuttle vectors for constructing environmental libraries and detecting heterologous natural products in multiple expression hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Metabolic flux analysis and pharmaceutical production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Synthetic protein scaffolds provide modular control over metabolic flux.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Stabilized gene duplication enables long-term selection-free heterologous pathway expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Establishment of a novel anabolism-based addiction system with an artificially introduced mevalonate pathway: complete stabilization of plasmids as universal application in white biotechnology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Solid-state fermentation: a promising microbial technology for secondary metabolite production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Solid-state fermentation systems-an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Exploitation of biological wastes for the production of value-added products under solid-state fermentation conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

A priority paper for the societal and ethical aspects of synthetic biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Synthetic biology in society: learning from past experience?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Ensuring the security of synthetic biology-towards a 5P governance strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Meetings that changed the world: Asilomar 1975: DNA modification secured.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Debottlenecking the 1,3-propanediol pathway by metabolic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

A literature review on the safety assessment of genetically modified plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Problems in monitoring horizontal gene transfer in field trials of transgenic plants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Regulation must be revolutionized

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Will the patentability of genes survive?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Chemistry: Enzyme expertise.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

Bridging data gaps in environmental assessments: Modeling impacts of fine and basic chemical production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NP00029B

21 January 2018

Identifiers

DOI

10.1039/C1NP00029B

1 reference

release_kelas52amjb7pegvoa63xpapim

24 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kelas52amjb7pegvoa63xpapim

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference