(Q48562250)

12 February 2018

title

Expression of the Alzheimer's Disease Mutations AβPP695sw and PSEN1M146I in Double-Transgenic Göttingen Minipigs. (English)

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12 February 2018

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6

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Carmela Matrone

9

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12 February 2018

Anders Nielsen

12

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12 February 2018

author name string

Jannik E Jakobsen

1

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12 February 2018

Marianne G Johansen

2

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12 February 2018

Mette Schmidt

3

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12 February 2018

Ying Liu

4

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12 February 2018

Rong Li

5

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12 February 2018

Margarita Melnikova

7

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12 February 2018

Mette Habekost

8

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12 February 2018

Yvonne Bouter

10

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12 February 2018

Thomas A Bayer

11

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12 February 2018

Monika Duthie

13

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12 February 2018

Paul E Fraser

14

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12 February 2018

Ida E Holm

15

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12 February 2018

Arne Lund Jørgensen

16

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12 February 2018

publication date

1 July 2016

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12 February 2018

Journal of Alzheimer's Disease

published in

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12 February 2018

volume

53

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12 February 2018

issue

4

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12 February 2018

page(s)

1617-1630

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12 February 2018

Genetically modified pigs to model human diseases

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1 reference

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Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs

21 January 2018

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Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth

21 January 2018

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The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs

21 January 2018

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21 January 2018

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Targeted disruption of LDLR causes hypercholesterolemia and atherosclerosis in Yucatan miniature pigs

21 January 2018

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21 January 2018

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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

21 January 2018

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21 January 2018

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21 January 2018

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

21 January 2018

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A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw

21 January 2018

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Elimination of the plasmid bacterial backbone in site-directed transgenesis

21 January 2018

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21 January 2018

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Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases

21 January 2018

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N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits

21 January 2018

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Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease

21 January 2018

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Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests.

21 January 2018

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A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade

21 January 2018

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Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease

21 January 2018

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Intraneuronal Abeta42 accumulation in human brain.

21 January 2018

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Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

21 January 2018

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Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice

21 January 2018

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The Arctic Alzheimer mutation facilitates early intraneuronal Abeta aggregation and senile plaque formation in transgenic mice.

21 January 2018

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Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

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Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

21 January 2018

1 reference

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Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

21 January 2018

1 reference

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Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

21 January 2018

1 reference

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Intracellular Aß triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160408

Transient intraneuronal A beta rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160408

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160408

Neuron loss in the 5XFAD mouse model of Alzheimer's disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160408

Intraneuronal Abeta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160408

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160408

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160408

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160408

Single App knock-in mouse models of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3233%2FJAD-160408

21 January 2018

Identifiers

DOI

10.3233/JAD-160408

1 reference

12 February 2018

release_bm3wrgomsbdm3ks5ycurfpcxzi

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bm3wrgomsbdm3ks5ycurfpcxzi

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

27540966

1 reference

12 February 2018