(Q50161371)

English

Hippocampal Mutant APP and Amyloid Beta Induced Cognitive Decline, Dendritic Spine Loss, Defective Autophagy, Mitophagy and Mitochondrial Abnormalities in a Mouse Model of Alzheimer's Disease.

scientific article published in February 2018

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 February 2018

http://europepmc.org/abstract/MED/29408999

Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

Alzheimer's disease

0 references

dendritic spine

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1

object named as

Maria Manczak

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

author name string

Ramesh Kandimalla

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

Xiangling Yin

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

P Hemachandra Reddy

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

publication date

1 February 2018

1 reference

Europe PubMed Central

PubMed publication ID

26 February 2018

http://europepmc.org/abstract/MED/29408999

Human Molecular Genetics

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

27

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

1332-1342

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of synaptic density in the septal nuclei of young and aged Fischer 344 rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perforant pathway changes and the memory impairment of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strain comparison of synaptic density in hippocampal CA1 of aged rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developments of a water-maze procedure for studying spatial learning in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deterioration threshold of synaptic morphology in aging and senile dementia of Alzheimer's type.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural correlates of cognition in dementia: quantification and assessment of synapse change.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for vibratome sectioning of Golgi-Cox stained whole rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative damage is the earliest event in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Alzheimer's disease mitochondrial cascade hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synapses, synaptic activity and intraneuronal abeta in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain aging, Alzheimer's disease, and mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased neuronal PreP activity reduces Aβ accumulation, attenuates neuroinflammation and improves mitochondrial and synaptic function in Alzheimer disease's mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidants Rescue Mitochondrial Transport in Differentiated Alzheimer's Disease Trans-Mitochondrial Cybrid Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Dysfunction Triggers Synaptic Deficits via Activation of p38 MAP Kinase Signaling in Differentiated Alzheimer's Disease Trans-Mitochondrial Cybrid Cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29408999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDY042

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6455948&resulttype=core&format=json

13 May 2020

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