(Q50529262)

14 March 2018

review article

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title

Gifted microbes for genome mining and natural product discovery. (English)

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14 March 2018

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Richard H Baltz

1

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14 March 2018

publication date

12 August 2016

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14 March 2018

Journal of Industrial Microbiology & Biotechnology

published in

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14 March 2018

volume

44

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14 March 2018

page(s)

573-588

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14 March 2018

issue

4-5

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14 March 2018

Genome mining of Streptomyces ambofaciens.

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Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?

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Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery

21 January 2018

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MbtH homology codes to identify gifted microbes for genome mining.

21 January 2018

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Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes

21 January 2018

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Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary

21 January 2018

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Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products

21 January 2018

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Draft Genome Sequence of Streptomyces rapamycinicus Strain NRRL 5491, the Producer of the Immunosuppressant Rapamycin

21 January 2018

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Taxonomy, Physiology, and Natural Products of Actinobacteria

21 January 2018

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Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

21 January 2018

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Bioactive microbial metabolites

21 January 2018

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antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers

21 January 2018

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Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides

21 January 2018

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Unusual biology across a group comprising more than 15% of domain Bacteria.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Natural product and natural product derived drugs in clinical trials.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways

21 January 2018

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Global biogeographic sampling of bacterial secondary metabolism

21 January 2018

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Illuminating the dark matter in metabolomics

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Importance of microbial natural products and the need to revitalize their discovery

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

A roadmap for natural product discovery based on large-scale genomics and metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genomic insights to SAR86, an abundant and uncultivated marine bacterial lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

New insights into chloramphenicol biosynthesis in Streptomyces venezuelae ATCC 10712.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Natural product derived insecticides: discovery and development of spinetoram

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Microbial natural products: molecular blueprints for antitumor drugs.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Metabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid Monomer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Evolution of sensory complexity recorded in a myxobacterial genome

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

IMG-ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Draft Genome Sequence of Uncultured SAR324 Bacterium lautmerah10, Binned from a Red Sea Metagenome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Metagenomic discovery of biomass-degrading genes and genomes from cow rumen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Identification and activation of novel biosynthetic gene clusters by genome mining in the kirromycin producer Streptomyces collinus Tü 365.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

The complete genomic sequence of Nocardia farcinica IFM 10152

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Untangling genomes from metagenomes: revealing an uncultured class of marine Euryarchaeota

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Informatic search strategies to discover analogues and variants of natural product archetypes.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Small genomes and sparse metabolisms of sediment-associated bacteria from four candidate phyla

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Natural product discovery: past, present, and future

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Culture-independent discovery of natural products from soil metagenomes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Discovery and development of surotomycin for the treatment of Clostridium difficile

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genome Sequence of Streptomyces toyocaensis NRRL 15009, Producer of the Glycopeptide Antibiotic A47934

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of Actinosynnema mirum type strain (101).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genome sequence of the halotolerant marine bacterium Myxococcus fulvus HW-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of Thermobispora bispora type strain (R51).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genome-guided discovery of diverse natural products from Burkholderia sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of Paenibacillus mucilaginosus 3016, a bacterium functional as microbial fertilizer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Advancing cell wall inhibitors towards clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

De novo metagenomic assembly reveals abundant novel major lineage of Archaea in hypersaline microbial communities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Natural Products as Sources of New Drugs from 1981 to 2014.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of Streptosporangium roseum type strain (NI 9100).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Mapping the tree of life: progress and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of Saccharomonospora viridis type strain (P101).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Insights into the phylogeny and coding potential of microbial dark matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of the kirromycin producer Streptomyces collinus Tü 365 consisting of a linear chromosome and two linear plasmids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genome sequence of the 1,4-dioxane-degrading Pseudonocardia dioxanivorans strain CB1190.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of the myxobacterium Sorangium cellulosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Leveraging ecological theory to guide natural product discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of Saccharothrix espanaensis DSM 44229(T) and comparison to the other completely sequenced Pseudonocardiaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Activation and products of the cryptic secondary metabolite biosynthetic gene clusters by rifampin resistance (rpoB) mutations in actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Identifying producers of antibacterial compounds by screening for antibiotic resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Antibiotic resistance-mediated isolation of scaffold-specific natural product producers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of Nakamurella multipartita type strain (Y-104).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Computational strategies for genome-based natural product discovery and engineering in fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genomic insights into the distribution, genetic diversity and evolution of polyketide synthases and nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Strategies for mining fungal natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genomic and transcriptomic insights into the thermo-regulated biosynthesis of validamycin in Streptomyces hygroscopicus 5008.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Insights into naturally minimised Streptomyces albus J1074 genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Triggers and cues that activate antibiotic production by actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-016-1815-X

Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM)

21 January 2018

1 reference

12 December 2020

Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the spiramycin producer

1 reference

12 December 2020

Phylogenetic identification and in situ detection of individual microbial cells without cultivation

1 reference

12 December 2020

Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases

1 reference

12 December 2020

Complete genome sequence of the motile actinomycete Actinoplanes missouriensis 431(T) (= NBRC 102363(T))

1 reference

12 December 2020

10.1007/S10295-016-1815-X

Identifiers

DOI

1 reference

14 March 2018

PubMed ID

27520548

1 reference

14 March 2018