(Q52667625)

English

gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo.

scientific article published in May 2006

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scholarly article

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

retracted paper

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Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo. (English)

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

author name string

Laura E Doglio

1

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

Ritu Kanwar

2

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

George R Jackson

3

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

Mar Perez

4

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

Jesús Avila

5

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

Colin Dingwall

6

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

Carlos G Dotti

7

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

Mark E Fortini

8

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

Fabián Feiguin

9

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

language of work or name

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publication date

1 May 2006

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

50

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

3

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

359-375

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

Drosophila nicastrin is essential for the intramembranous cleavage of notch

1 reference

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Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor

1 reference

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Mutant genes in familial Alzheimer's disease and transgenic models

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Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.

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Tau is essential to beta -amyloid-induced neurotoxicity

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Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex

1 reference

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Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

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PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations

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Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

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Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster

1 reference

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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

1 reference

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Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

1 reference

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Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

1 reference

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New frontiers in Alzheimer's disease genetics

1 reference

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1 reference

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Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

1 reference

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Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

1 reference

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Drosophila as a model for human neurodegenerative disease

1 reference

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

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An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.

1 reference

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Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins.

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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Mouse and fly models of neurodegeneration

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GSK-3 dependent phosphoepitopes recognized by PHF-1 and AT-8 antibodies are present in different tau isoforms

1 reference

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Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.1016/J.NEURON.2006.03.038

Presenilins in memory, Alzheimer's disease, and therapy

1 reference

9 February 2024

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Alzheimer's disease: genetic studies and transgenic models

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Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

1 reference

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Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity

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Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

1 reference

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Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

1 reference

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Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration.

1 reference

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PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila.

1 reference

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Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

1 reference

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wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate

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A versatile transcriptional effector of Wingless signaling

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Neuronal development in the Drosophila retina: monoclonal antibodies as molecular probes.

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Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.

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Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

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Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.

1 reference

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Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants

1 reference

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A presenilin-1 truncating mutation is present in two cases with autopsy-confirmed early-onset Alzheimer disease

1 reference

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Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2

1 reference

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A novel presenilin 1 mutation associated with Pick's disease but not beta-amyloid plaques.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.1016/J.NEURON.2006.03.038

Identifiers

10.1016/J.NEURON.2006.03.038

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

1 reference

Europe PubMed Central

5 May 2018

http://europepmc.org/abstract/MED/16675392

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