(Q53288810)

13 May 2018

title

Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumor suppressor genes. (English)

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13 May 2018

author

Dobril Ivanov

1

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13 May 2018

David N. Cooper

6

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13 May 2018

Nadia Chuzhanova

7

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13 May 2018

Hildegard Kehrer-Sawatzki

5

object named as

Hildegard Kehrer-Sawatzki

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13 May 2018

author name string

Stephen E Hamby

2

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13 May 2018

Peter D Stenson

3

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13 May 2018

Andrew D Phillips

4

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13 May 2018

publication date

22 March 2011

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13 May 2018

published in

Human Mutation

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13 May 2018

volume

32

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13 May 2018

issue

6

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13 May 2018

page(s)

620-632

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13 May 2018

Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

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The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis

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APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'.

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DNA slippage occurs at microsatellite loci without minimal threshold length in humans: a comparative genomic approach

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Analysis of germline mutation spectra at the Huntington's disease locus supports a mitotic mutation mechanism

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Complex patterns of male germline instability and somatic mosaicism in myotonic dystrophy type 1.

21 January 2018

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Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

21 January 2018

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21 January 2018

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21 January 2018

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Design and analysis issues in genome-wide somatic mutation studies of cancer

21 January 2018

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Replication-mediated instability of the GAA triplet repeat mutation in Friedreich ataxia

21 January 2018

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Sensitive and efficient detection of RB1 gene mutations enhances care for families with retinoblastoma

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21 January 2018

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21 January 2018

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Characterization of the somatic mutational spectrum of the neurofibromatosis type 1 (NF1) gene in neurofibromatosis patients with benign and malignant tumors.

21 January 2018

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Cancer genes and the pathways they control

21 January 2018

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Evolutionary conservation and somatic mutation hotspot maps of p53: correlation with p53 protein structural and functional features.

21 January 2018

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Sample size and power estimation for studies with health related quality of life outcomes: a comparison of four methods using the SF-36

21 January 2018

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https://api.crossref.org/works/10.1002%2FHUMU.21483

Meta-analysis of indels causing human genetic disease: mechanisms of mutagenesis and the role of local DNA sequence complexity

21 January 2018

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Somatic spectrum of cancer-associated single basepair substitutions in the TP53 gene is determined mainly by endogenous mechanisms of mutation and by selection

21 January 2018

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https://api.crossref.org/works/10.1002%2FHUMU.21483

Germline and somaticNF1 gene mutation spectrum in NF1-associated malignant peripheral nerve sheath tumors (MPNSTs)

21 January 2018

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Detailed computational study of p53 and p16: using evolutionary sequence analysis and disease-associated mutations to predict the functional consequences of allelic variants

21 January 2018

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Analysis of (CAG)n size heterogeneity in somatic and sperm cell DNA from intermediate and expanded Huntington disease gene carriers

21 January 2018

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7 January 2021

Mutation hotspots in the p53 gene in tumors of different origin: correlation with evolutionary conservation and signs of positive selection

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7 January 2021

Tumour-suppressor genes: evolving definitions in the genomic age

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7 January 2021

Germline APC mutation spectrum derived from 863 genomic variations identified through a 15-year medical genetics service to French patients with FAP

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https://api.crossref.org/works/10.1002%2FHUMU.21483

7 January 2021

Germline versus somatic mutations of the APC gene: evidence for mechanistic differences

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https://api.crossref.org/works/10.1002%2FHUMU.21483

7 January 2021

The GAA triplet-repeat sequence in Friedreich ataxia shows a high level of somatic instability in vivo, with a significant predilection for large contractions

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https://api.crossref.org/works/10.1002%2FHUMU.21483

7 January 2021

Allele diversity and germline mutation at the insulin minisatellite

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7 January 2021

Identifiers

DOI

10.1002/HUMU.21483

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13 May 2018

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13 May 2018