(Q53353140)

13 May 2018

title

Self-association of adenovirus type 5 E1B-55 kDa as well as p53 is essential for their mutual interaction. (English)

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13 May 2018

1 reference

Magdalena E. Morawska

series ordinal

1

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13 May 2018

Matthias Dobbelstein

series ordinal

3

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13 May 2018

Krystyna Bieńkowska-Szewczyk

series ordinal

2

object named as

K Bieńkowska-Szewczyk

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13 May 2018

language of work or name

English

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publication date

21 December 2009

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13 May 2018

published in

Oncogene

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13 May 2018

volume

29

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13 May 2018

issue

12

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13 May 2018

page(s)

1773-1786

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/onc.2009.461

exact match

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cites work

Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes

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Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation

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Four p53 DNA-binding domain peptides bind natural p53-response elements and bend the DNA.

21 January 2018

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Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus

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Post-translational modification of p53 in tumorigenesis

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The role of tetramerization in p53 function

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Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex

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IgM--molecular requirements for its assembly and function

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Human Rad50/Mre11 is a flexible complex that can tether DNA ends

21 January 2018

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Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence

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Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor

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Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes

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Effects of mutations in the adenoviral E1B 55-kilodalton protein coding sequence on viral late mRNA metabolism.

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The quaternary structure of the adenovirus 12 early region 1B 54K protein

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Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery

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Mdm2 promotes the rapid degradation of p53

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Coping with stress: multiple ways to activate p53.

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Regulation of p53 stability by Mdm2

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Regulation of Mdm2-directed degradation by the C terminus of p53.

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The adenovirus type 5 E1b 55K and E4 Orf3 proteins associate in infected cells and affect ND10 components

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The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53.

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Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor

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Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

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Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex

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Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2

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RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis

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Recent advances in p53 research: an interdisciplinary perspective.

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Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

21 January 2018

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Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex

21 January 2018

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Distinct requirements of adenovirus E1b55K protein for degradation of cellular substrates

21 January 2018

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Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

21 January 2018

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Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein

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Hetero-oligomerization with MdmX rescues the ubiquitin/Nedd8 ligase activity of RING finger mutants of Mdm2.

21 January 2018

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Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex

21 January 2018

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E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.461

Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.461

Sequestration of p53 in the cytoplasm by adenovirus type 12 E1B 55-kilodalton oncoprotein is required for inhibition of p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.461

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.461

The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.461

Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.461

inferred from DOI database lookup

7 January 2021

based on heuristic

Adenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.461

inferred from DOI database lookup

7 January 2021

based on heuristic

Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.461

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ONC.2009.461

1 reference

13 May 2018

Dimensions Publication ID

0 references

1 reference

13 May 2018