(Q54659609)

2 June 2018

title

Pregnancy and pharmacogenomics in the context of drug metabolism and response. (English)

1 reference

2 June 2018

1 reference

Anders Helldén

1

0 references

author name string

Parvaz Madadi

series ordinal

2

1 reference

2 June 2018

publication date

1 November 2013

1 reference

2 June 2018

published in

Pharmacogenomics

1 reference

2 June 2018

volume

14

1 reference

2 June 2018

issue

14

1 reference

2 June 2018

page(s)

1779-1791

1 reference

2 June 2018

Medication use during pregnancy, with particular focus on prescription drugs: 1976-2008.

cites work

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

The increasing prevalence of diabetes in pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Anatomical, physiological and metabolic changes with gestational age during normal pregnancy: a database for parameters required in physiologically based pharmacokinetic modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Serum cystatin C for assessment of glomerular filtration rate in pregnant and non-pregnant women. Indications of altered filtration process in pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Physiological changes of pregnancy and monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Antiepileptic drug treatment in pregnancy: changes in drug disposition and their clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Temporal changes in drug metabolism (CYP1A2, CYP2D6 and CYP3A Activity) during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Alterations in drug disposition during pregnancy: implications for drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Isoform-specific regulation of cytochromes P450 expression by estradiol and progesterone

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Induction of hepatic CYP3A enzymes by pregnancy-related hormones: studies in human hepatocytes and hepatic cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pregnancy-induced changes in pharmacokinetics: a mechanistic-based approach

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Cytochrome p450 and chemical toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Cytochrome P450 enzymes in the brain: emerging evidence of biological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

The function of cytochrome P450 1A1 enzyme (CYP1A1) and aryl hydrocarbon receptor (AhR) in the placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

CYP1A in TCDD toxicity and in physiology-with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Association of CYP1A1 gene polymorphism with recurrent pregnancy loss in the South Indian population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

The effect of pregnancy on cytochrome P4501A2, xanthine oxidase, and N-acetyltransferase activities in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Caffeine metabolism, genetics, and perinatal outcomes: a review of exposure assessment considerations during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Caffeine, selected metabolic gene variants, and risk for neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Stillbirth and slow metabolizers of caffeine: comparison by genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Polymorphisms of CYP2A6 and its practical consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Accelerated metabolism of nicotine and cotinine in pregnant smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacogenomics of maternal tobacco use: metabolic gene polymorphisms and risk of adverse pregnancy outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Quantitative prediction of CYP2B6 induction by estradiol during pregnancy: potential explanation for increased methadone clearance during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Estradiol induces cytochrome P450 2B6 expression at high concentrations: implication in estrogen-mediated gene regulation in pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacologic evidence to support clinical decision making for peripartum methadone treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Influence of CYP2B6 polymorphisms on the persistence of plasma nevirapine concentrations following a single intra-partum dose for the prevention of mother to child transmission in HIV-infected Thai women

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part I.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacokinetics of anticonvulsants in pregnancy: alterations in plasma protein binding

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Clinical significance of the cytochrome P450 2C19 genetic polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Increased omeprazole metabolism in carriers of the CYP2C19*17 allele; a pharmacokinetic study in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Are proton pump inhibitors safe during pregnancy and lactation? Evidence to date

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacogenetics of opioids for the treatment of acute maternal pain during pregnancy and lactation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Potential role of CYP2D6 in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Serum nortriptyline levels in nursing mothers and their infants.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Changes in antidepressant metabolism and dosing across pregnancy and early postpartum

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Effect of cytochrome P450 2D6 genotype on maternal paroxetine plasma concentrations during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Identification of cytochrome P450 isoforms involved in the metabolism of paroxetine and estimation of their importance for human paroxetine metabolism using a population-based simulator

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

CYP2E1 and oxidative liver injury by alcohol

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

The human intestinal cytochrome P450 "pie".

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A7*1C allele

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Genetic predictors of interindividual variability in hepatic CYP3A4 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Value of CYP3A5 genotyping on determining initial dosages of tacrolimus for Chinese renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacokinetics of saquinavir plus low-dose ritonavir in human immunodeficiency virus-infected pregnant women

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacokinetics of saquinavir-SGC in HIV-infected pregnant women

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacokinetics of tacrolimus during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Regulation of phase II biotransformation enzymes by steroid hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

The glycosidation of xenobiotics and endogenous compounds: versatility and redundancy in the UDP glycosyltransferase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Regulation of UDP-glucuronosyltransferase (UGT) 1A1 by progesterone and its impact on labetalol elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Function, genetic polymorphism, and transcriptional regulation of human UDP-glucuronosyltransferase (UGT) 1A1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Up-regulation of UDP-glucuronosyltransferase (UGT) 1A4 by 17beta-estradiol: a potential mechanism of increased lamotrigine elimination in pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Lamotrigine clearance during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Gestation-induced changes in lamotrigine pharmacokinetics: a monotherapy study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

The impact of pregnancy and childbirth on the metabolism of lamotrigine.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Lamotrigine in pregnancy: clearance, therapeutic drug monitoring, and seizure frequency

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Prospectively assessed changes in lamotrigine-concentration in women with epilepsy during pregnancy, lactation and the neonatal period.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Severe apnea in an infant exposed to lamotrigine in breast milk

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Polymorphisms of human N-acetyltransferases and cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacogenetics in reproductive and perinatal medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

N-acetyl-transferase phenotype and risk for preeclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Efflux transporters of the human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

P-glycoprotein in the placenta: expression, localization, regulation and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Drug transporters in the human blood-placental barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacotherapy in pregnancy; effect of ABC and SLC transporters on drug transport across the placenta and fetal drug exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Genetic polymorphisms of the human MDR1 drug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Impact of OATP transporters on pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Effects of pregnancy on CYP3A and P-glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Prediction of codeine toxicity in infants and their mothers using a novel combination of maternal genetic markers.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Pharmacokinetics of metformin during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Liver diseases unique to pregnancy: a 2010 update

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

The spectrum of liver diseases related to ABCB4 gene mutations: pathophysiology and clinical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Endocrine and metabolic regulation of renal drug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Hepatobiliary transporters and drug-induced cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.13.176

21 January 2018

Identifiers

DOI

10.2217/PGS.13.176

1 reference

2 June 2018

1 reference

2 June 2018