(Q55360325)

3 July 2018

title

RNA interference. Drugging RNAi. (English)

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3 July 2018

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Dirk Haussecker

1

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3 July 2018

Mark A Kay

series ordinal

2

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3 July 2018

language of work or name

English

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publication date

1 March 2015

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3 July 2018

published in

Science

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3 July 2018

volume

347

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3 July 2018

issue

6226

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3 July 2018

page(s)

1069-1070

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3 July 2018

Current issues of RNAi therapeutics delivery and development

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

The Business of RNAi Therapeutics in 2012

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

Improved specificity of gene silencing by siRNAs containing unlocked nucleobase analogs

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

Safety and efficacy of RNAi therapy for transthyretin amyloidosis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

Sustained miRNA-mediated knockdown of mutant AAT with simultaneous augmentation of wild-type AAT has minimal effect on global liver miRNA profiles.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6018011

Investment suggests RNAi is on the up

12 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25745148

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1252967

1 reference

3 July 2018

PMC publication ID

6018011

1 reference

3 July 2018

PubMed publication ID

25745148

1 reference

3 July 2018